Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.50 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.45 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.39 |
| ▸ | ESRRB | O95718 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESRRA | P11474 | 1/20 | 0.39 |
| ▸ | ESRRG | P62508 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 3/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | AGER | Q15109 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10088897 | 0.80 | CTSS (0.55) | MRGPRX4SSTR4TRPV4SCN9ACTSS | |
| SCHEMBL506595 | 0.77 | ALDH1A1 (0.42) | ESRRAPTGDR2 | |
| SCHEMBL23578526 | 0.77 | MRGPRX4 (0.50) | MRGPRX4SSTR4TRPV4SCN9ACTSS | |
| SCHEMBL3496978 | 0.77 | XDH (0.52) | MRGPRX4SSTR4TRPV4SCN9AESRRB | |
| SCHEMBL22140450 | 0.77 | TRPV4 (0.43) | SSTR4TRPV4KIF11 | |
| SCHEMBL6248816 | 0.75 | MRGPRX4 (0.55) | MRGPRX4SSTR4TRPV4SCN9ACTSS | |
| SCHEMBL21728097 | 0.75 | AR (0.44) | MRGPRX4TRPV4PTGDR2 | |
| SCHEMBL28857557 | 0.75 | HPGD (0.40) | TRPV4PTGDR2 | |
| SCHEMBL22731288 | 0.74 | TRPV4 (0.49) | MRGPRX4SSTR4TRPV4SCN9AESRRB | |
| SCHEMBL523319 | 0.74 | ESRRB (0.51) | MRGPRX4TRPV4ESRRBESR1ESRRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011035900-A1 | NEW THIADIAZOLE DERIVATIVES | ALMIRALL, S.A. (ES) | 2011-03-31 | — | — | WO | disclosed |
| WO-2011035900-A1 | NEW THIADIAZOLE DERIVATIVES | ALMIRALL, S.A. (ES) | 2011-03-31 | — | — | WO | disclosed |