Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 11/20 | 0.50 |
| ▸ | MET | P08581 | 9/20 | 0.50 |
| ▸ | CTSC | P53634 | 1/20 | 0.48 |
| ▸ | SYK | P43405 | 2/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | MERTK | Q12866 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.42 |
| ▸ | STK17B | O94768 | 1/20 | 0.42 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL541915 | 0.85 | ALK (0.69) | ALKMET | |
| SCHEMBL14899917 | 0.83 | ALK (0.50) | ALKMETCTSCSYKBRD4 | |
| SCHEMBL30833724 | 0.78 | ALK (0.52) | ALKMETSYKNTRK1MAPK9 | |
| SCHEMBL30833649 | 0.76 | CDK9 (0.47) | ALKMETMAPK9MAPK10 | |
| SCHEMBL30833714 | 0.76 | ALK (0.46) | ALKMETSYKAXLMAPK9 | |
| SCHEMBL30833696 | 0.76 | ALK (0.52) | ALKMETMAPK9MAPK10 | |
| SCHEMBL1035873 | 0.76 | ALK (0.67) | ALKMETSYK | |
| SCHEMBL30833643 | 0.75 | ALK (0.43) | ALKMETMAPK9MAPK10 | |
| SCHEMBL30833776 | 0.75 | ALK (0.48) | ALKMETSYK | |
| SCHEMBL30833757 | 0.75 | ALK (0.47) | ALKMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414337-B1 | Methods for the identification of kinase interacting molecules and for the purification of kinase proteins | CELLZOME GMBH (DE) | 2013-05-01 | — | — | EP | disclosed |