Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 3/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.47 |
| ▸ | CDK2 | P24941 | 2/20 | 0.47 |
| ▸ | CCNK | O75909 | 1/20 | 0.47 |
| ▸ | CCND3 | P30281 | 1/20 | 0.47 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.47 |
| ▸ | ALK | Q9UM73 | 8/20 | 0.45 |
| ▸ | MET | P08581 | 5/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 2/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | CDK7 | P50613 | 2/20 | 0.40 |
| ▸ | ULK1 | O75385 | 1/20 | 0.40 |
| ▸ | INSR | P06213 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833772 | 0.83 | CDK2 (0.46) | CDK9CCNA2CDK2CCNKCCND3 | |
| SCHEMBL29190618 | 0.81 | ALK (0.59) | CDK9CCNA2CDK2CCNKCCND3 | |
| SCHEMBL30833643 | 0.80 | ALK (0.43) | CDK9ALKMETMAPK9MAPK10 | |
| SCHEMBL29190576 | 0.77 | CDK2 (0.53) | CDK9CCNA2CDK2CCNKCCND3 | |
| SCHEMBL30833804 | 0.77 | CDK2 (0.53) | CDK9CCNA2CDK2CCNKCCND3 | |
| SCHEMBL14889458 | 0.76 | ALK (0.50) | ALKMETMAPK9MAPK10 | |
| SCHEMBL30833724 | 0.75 | ALK (0.52) | CDK9CDK2ALKMETMAPK9 | |
| SCHEMBL26906809 | 0.71 | ALK (0.48) | CDK9CCNA2CDK2CCNKCCND3 | |
| SCHEMBL29904714 | 0.71 | ALK (0.48) | CDK9CCNA2CDK2CCNKCCND3 | |
| SCHEMBL30833733 | 0.69 | PIN1 (0.36) | CDK9ALKAURKAAURKBCDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |