Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 4/20 | 0.43 |
| ▸ | CDK7 | P50613 | 10/20 | 0.41 |
| ▸ | CDK9 | P50750 | 9/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.39 |
| ▸ | BCL6 | P41182 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | INSR | P06213 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833659 | 0.88 | AURKA (0.48) | ALKCDK7CDK9TRPV1MAPK8 | |
| SCHEMBL30833733 | 0.88 | PIN1 (0.36) | ALKCDK7CDK9TRPV1AURKA | |
| SCHEMBL30833796 | 0.88 | IGF1R (0.46) | ALKCDK7CDK9TRPV1MAPK8 | |
| SCHEMBL30833765 | 0.88 | PKMYT1 (0.38) | ALKCDK7CDK9TRPV1AURKA | |
| SCHEMBL29904714 | 0.87 | ALK (0.48) | ALKCDK7CDK9MAPK8BCL6 | |
| SCHEMBL26906809 | 0.87 | ALK (0.48) | ALKCDK7CDK9MAPK8BCL6 | |
| SCHEMBL27238023 | 0.85 | ALK (0.40) | ALKCDK7CDK9MAPK8MAPK9 | |
| SCHEMBL30833703 | 0.84 | TRPV1 (0.47) | CDK7CDK9TRPV1AURKB | |
| SCHEMBL29904758 | 0.83 | ALK (0.41) | ALKMAPK9MAPK10INSR | |
| SCHEMBL2061884 | 0.82 | BPTF (0.44) | ALKCDK7CDK9MAPK8MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |