SCHEMBL14890281

SCHEMBL14890281

COc1ccc(C=C(CCC[Si](OC)(OC)OC)C(N)=O)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.40
THRB P10828 2/20 0.40
GSK3B P49841 1/20 0.40
KDM4E B2RXH2 3/20 0.40
ALDH1A1 P00352 2/20 0.40
HPGD P15428 2/20 0.40
RAB9A P51151 2/20 0.39
NPC1 O15118 1/20 0.39
F3 P13726 1/20 0.39
LMNA P02545 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
PARP1 P09874 1/20 0.38
PARP10 Q53GL7 1/20 0.38
PARP2 Q9UGN5 1/20 0.38
PARP4 Q9UKK3 1/20 0.38
GLO1 Q04760 3/20 0.38
CYP1A2 P05177 2/20 0.38
CYP3A4 P08684 1/20 0.38
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2010386 0.88 RECQL (0.41) MAPTTHRBLMNACYP3A4
SCHEMBL5269738 0.76 CYP3A4 (0.47) MAPTTHRBLMNACYP3A4APEX1
SCHEMBL4316822 0.72
SCHEMBL3156218 0.71 ALOX5 (0.46) MAPTTHRBGSK3BKDM4EALDH1A1
SCHEMBL3156208 0.71 ALOX5 (0.46) MAPTTHRBGSK3BKDM4EALDH1A1
SCHEMBL6367852 0.71 ALOX5 (0.58) MAPTTHRBGSK3BRAB9ANPC1
SCHEMBL12469698 0.71 PPARG (0.44) MAPTTHRBGSK3BKDM4EALDH1A1
SCHEMBL16797477 0.71 ALDH1A1 (0.53) MAPTTHRBGSK3BKDM4EALDH1A1
SCHEMBL3142281 0.70 CNR1 (0.47) MAPTTHRBGSK3BKDM4EALDH1A1
SCHEMBL3142273 0.70 CNR1 (0.47) MAPTTHRBGSK3BKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8921505-B2 Ultraviolet absorbing poly (organic oxidized silicon) particles having improved ultraviolet stability, and method for preparing same NANO AND MICRO TECHNOLOGIES CO., LTD. (KR) 2014-12-30 US disclosed
US-20130109824-A1 ULTRAVIOLET ABSORBING POLY (ORGANIC OXIDIZED SILICON) PARTICLES HAVING IMPROVED ULTRAVIOLET STABILITY, AND METHOD FOR PREPARING SAME NANO AND MICRO TECHNOLOGIES CO., LTD. (KR) 2013-05-02 US disclosed