Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Acrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.32 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL3176462 | 0.97 | TSHR (0.41) | TSHRACACBZDHHC20ZDHHC2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL127416 | 0.93 | TSHR (0.47) | TSHRACACBZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL309296 | 0.91 | TSHR (0.48) | TSHRACACBZDHHC20ZDHHC2ALDH1A1 | |
| Iodide SCHEMBL3132818 | 0.90 | TSHR (0.47) | TSHRACACBZDHHC20ZDHHC2ALDH1A1 | |
| Fluoride Ion SCHEMBL17105891 | 0.90 | TSHR (0.47) | TSHRACACBZDHHC20ZDHHC2ALDH1A1 | |
| Water SCHEMBL2355005 | 0.90 | TSHR (0.47) | TSHRACACBZDHHC20ZDHHC2ALDH1A1 | |
| Bromide SCHEMBL17105893 | 0.90 | TSHR (0.47) | TSHRACACBZDHHC20ZDHHC2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL26669427 | 0.90 | TSHR (0.47) | TSHRACACBZDHHC20ZDHHC2ALDH1A1 | |
| Methacrylic Acid SCHEMBL4236932 | 0.89 | TSHR (0.38) | TSHRACACB | |
| Chloromethane SCHEMBL27393559 | 0.88 | TSHR (0.45) | TSHRACACBZDHHC20ZDHHC2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 750 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111343964-A | Aqueous hair care compositions and methods | 因诺斯佩克有限公司 | 2020-06-26 | — | — | CN | claimed |
| US-8741961-B2 | Use of pargyline for the treatment of hair follicles | CUTECH S.R.L. (IT) | 2014-06-03 | — | — | US | claimed |
| EP-1242172-B1 | USE OF NANOSCALE POLYMERS | COGNIS DEUTSCHLAND GMBH (DE) | 2003-10-15 | — | — | EP | claimed |
| US-20030086894-A1 | Use of nanoscale polymers | COGNIS DEUTSCHLAND GMBH & GO. KG (DE) | 2003-05-08 | — | — | US | claimed |
| US-20240237643-A1 | COMPOSITIONS WITH VIRUCIDAL AND/OR ANTIVIRAL ACTIVITY | SYMRISE AG (DE) | 2024-07-18 | — | — | US | disclosed |
| US-20240216248-A1 | MICROBIAL GLYCOLIPIDS | ANALYTICON DISCOVERY GMBH (DE) | 2024-07-04 | — | — | US | disclosed |
| US-12023396-B2 | Flavour and fragrance compositions comprising acetophenone derivatives | SYMRISE AG (DE) | 2024-07-02 | — | — | US | disclosed |
| EP-4387587-A1 | COMPOSITIONS | Symrise AG (DE) | 2024-06-26 | — | — | EP | disclosed |
| US-12016944-B2 | Mixtures comprising a protein extract for the treatment of human skin and/or hair | SYMRISE AG (DE) | 2024-06-25 | — | — | US | disclosed |
| CN-118141701-A | Composition containing benzoic acid derivative or furoic acid derivative and use of the derivative for emulsion and foam stability | 西姆莱斯股份公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-118159632-A | Perfume and perfume mixture | 西姆莱斯股份公司 | 2024-06-07 | — | — | CN | disclosed |
| US-20240173227-A1 | A FRAGRANCE MIXTURE CONTAINING ISOCITRONELLOL | SYMRISE AG (DE) | 2024-05-30 | — | — | US | disclosed |
| US-20020010114-A1 | Water-based cleansing compositions | COGNIS DEUTSCHLAND GMBH & CO. KG (DE) | 2002-01-24 | — | — | US | disclosed |
| US-6316030-B1 | ABSORPTION, IN COSMETICS AND DRUGS | COGNIS DEUTSCHLAND GMBH (DE) | 2001-11-13 | — | — | US | disclosed |
| US-6306410-B1 | SKIN CLEANSERS FOR REMOVING DECORATIVE SKIN MAKEUP | COGNIS DEUTSCHLAND GMBH (DE) | 2001-10-23 | — | — | US | disclosed |
| US-6300297-B1 | Hard soap containing fatty acid polyglycol ester sulphates | COGNIS DEUTSCHLAND GMBH (DE) | 2001-10-09 | — | — | US | disclosed |
| US-6277359-B1 | (A) A GEMINI SURFACTANT OF A DIMER OR TRIMER ALCOHOL SULFATE; (B) ALUMINUM CHLOROHYDRATE; AND (C) AN ESTERASE INHIBITOR, A BACTERICIDAL AGENT, OR A BACTERIOSTATIC AGENT | COGNIS DEUTSCHLAND GMBH (DE) | 2001-08-21 | — | — | US | disclosed |
| US-6146619-A | HAIR PERMANENT WITH A COMBINATION OF ACTIVE SUBSTANCES; CAN BE USE FOR STRAIGHTENING NATURALLY CURLED OR CHEMICALLY WAVED HAIR | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2000-11-14 | — | — | US | disclosed |
| US-6126921-A | Hair treatment formulations containing a water-insoluble polymer having a glass transition temperature of -20° C. to 70° C. | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2000-10-03 | — | — | US | disclosed |
| US-5830483-A | GLYCEROL OR POLYGLYCEROL ALKYL GLUCOSIDE FATTY ESTER | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1998-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12023396-B2 | Flavour and fragrance compositions comprising acetophenone derivatives | FAAH2, ADH5, NISCH | TSHR 4797/4885ACACB 81/4885ZDHHC20 63/4885 |
| US-20240216248-A1 | MICROBIAL GLYCOLIPIDS | UGCG, SGMS1, GPR119 | TSHR 1762/4885ACACB 601/4885ZDHHC20 101/4885 |
| US-20240237643-A1 | COMPOSITIONS WITH VIRUCIDAL AND/OR ANTIVIRAL ACTIVITY | ZC3HAV1, SAMHD1, ZC3HAV1L | TSHR 4680/4885ACACB 3920/4885ZDHHC20 923/4885 |
| US-20020010114-A1 | Water-based cleansing compositions | LIPA, WASHC4, WASHC5 | TSHR 3016/4885ACACB 623/4885ZDHHC20 109/4885 |
| US-20240173227-A1 | A FRAGRANCE MIXTURE CONTAINING ISOCITRONELLOL | IPO5, OR51E2, FDFT1 | TSHR 4320/4885ACACB 2793/4885ZDHHC20 159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.