Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | MC5R | P33032 | 1/20 | 0.31 |
| ▸ | MC3R | P41968 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2668708 | 0.92 | SLC6A2 (0.37) | TRPV1KCNH2 | |
| SCHEMBL14899708 | 0.88 | TRPV1 (0.35) | RAB9AALDH1A1TRPV1KCNH2LMNA | |
| SCHEMBL9071949 | 0.87 | ALDH1A1 (0.41) | ALDH1A1KCNH2LMNATRPM8 | |
| SCHEMBL2668590 | 0.87 | ALDH1A1 (0.41) | ALDH1A1KCNH2LMNATRPM8 | |
| SCHEMBL2668517 | 0.82 | PYGL (0.41) | ALDH1A1KDM4EEPHX2SMN1; SMN2LMNA | |
| SCHEMBL13486496 | 0.81 | HTR2A (0.39) | — | |
| SCHEMBL12204361 | 0.79 | TRPM8 (0.39) | ALDH1A1KDM4EEPHX2MC4RMC5R | |
| SCHEMBL9071933 | 0.79 | MAOB (0.42) | ALDH1A1KDM4E | |
| SCHEMBL14899706 | 0.79 | MAOB (0.42) | ALDH1A1KDM4E | |
| SCHEMBL9071903 | 0.78 | KMT2A (0.42) | RAB9AALDH1A1TSHRPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904467-B1 | Urea glucokinase activators | NOVO NORDISK AS (DK) | 2013-05-01 | — | — | EP | disclosed |
| WO-2007006814-A1 | UREA GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2007-01-18 | — | — | WO | disclosed |