Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | CNR1 | P21554 | 1/20 | 0.64 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | F7 | P08709 | 3/20 | 0.55 |
| ▸ | F3 | P13726 | 3/20 | 0.55 |
| ▸ | PPARG | P37231 | 2/20 | 0.55 |
| ▸ | PPARD | Q03181 | 2/20 | 0.55 |
| ▸ | PPARA | Q07869 | 2/20 | 0.55 |
| ▸ | FABP3 | P05413 | 2/20 | 0.55 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.55 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12179604 | 1.00 | MGLL (0.66) | MGLLALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL14900573 | 0.96 | DNM1 (0.62) | MGLLALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL23587058 | 0.95 | MGLL (0.67) | MGLLALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL23686857 | 0.94 | MGLL (0.59) | MGLLALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL21363413 | 0.94 | MGLL (0.59) | MGLLALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL21235502 | 0.93 | MGLL (0.64) | MGLLALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL14759951 | 0.93 | MGLL (0.68) | MGLLALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL14759950 | 0.93 | MGLL (0.68) | MGLLALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL16104149 | 0.93 | MGLL (0.57) | MGLLALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL26551338 | 0.93 | MGLL (0.57) | MGLLALDH1A1MAPTTHRBCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3301086-A1 | PRODUCTION OF A COMPOSITION CONTAINING A COMPLEX BETWEEN A MEMBRANE COMPOSED OF A LIPID MONOLAYER AND A NUCLEIC ACID, AND, A LIPID MEMBRANE FOR ENCAPSULATING THE COMPLEX THEREIN | Kyowa Hakko Kirin Co., Ltd. (JP) | 2018-04-04 | — | — | EP | disclosed |
| US-9920028-B2 | Cationic lipid | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2018-03-20 | — | — | US | disclosed |
| US-9920028-B2 | Cationic lipid | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2018-03-20 | — | — | US | disclosed |
| US-9845306-B2 | Cationic lipid | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2017-12-19 | — | — | US | disclosed |
| US-9845306-B2 | Cationic lipid | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2017-12-19 | — | — | US | disclosed |
| US-20170349532-A1 | CATIONIC LIPID | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2017-12-07 | — | — | US | disclosed |
| US-20170349532-A1 | CATIONIC LIPID | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2017-12-07 | — | — | US | disclosed |
| US-20160304487-A1 | CATIONIC LIPID | KYOWA HAKKO KIRIN CO LTD (JP) | 2016-10-20 | — | — | US | disclosed |
| US-20160304487-A1 | CATIONIC LIPID | KYOWA HAKKO KIRIN CO LTD (JP) | 2016-10-20 | — | — | US | disclosed |
| US-9408914-B2 | Cationic lipid | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2016-08-09 | — | — | US | disclosed |
| US-9408914-B2 | Cationic lipid | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2016-08-09 | — | — | US | disclosed |
| US-20150343062-A1 | CATIONIC LIPID | KYOWA HAKKO KIRIN CO LTD (JP) | 2015-12-03 | — | — | US | disclosed |
| US-20150343062-A1 | CATIONIC LIPID | KYOWA HAKKO KIRIN CO LTD (JP) | 2015-12-03 | — | — | US | disclosed |
| US-20140045913-A1 | LIPID NANO PARTICLES COMPRISING COMBINATION OF CATIONIC LIPID | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2014-02-13 | — | — | US | disclosed |
| US-20140045913-A1 | LIPID NANO PARTICLES COMPRISING COMBINATION OF CATIONIC LIPID | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2014-02-13 | — | — | US | disclosed |
| US-20130280305-A1 | CATIONIC LIPID | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2013-10-24 | — | — | US | disclosed |
| US-20130280305-A1 | CATIONIC LIPID | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2013-10-24 | — | — | US | disclosed |
| WO-2013065825-A1 | CATIONIC LIPID | 協和発酵キリン株式会社 (JP) | 2013-05-10 | — | — | WO | disclosed |
| US-20130108685-A1 | CATIONIC LIPID | KYOWA KIRIN CO., LTD. (JP) | 2013-05-02 | — | — | US | disclosed |
| US-20130108685-A1 | CATIONIC LIPID | KYOWA KIRIN CO., LTD. (JP) | 2013-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160304487-A1 | CATIONIC LIPID | LPAR3, ACOX3, H1-3 | MGLL 80/4885ALDH1A1 3173/4885MAPT 4637/4885 |
| US-20140045913-A1 | LIPID NANO PARTICLES COMPRISING COMBINATION OF CATIONIC LIPID | LPAR3, APOL1, PLIN3 | MGLL 52/4885ALDH1A1 2814/4885MAPT 4116/4885 |
| US-20170349532-A1 | CATIONIC LIPID | LPAR3, ACOX3, H1-3 | MGLL 80/4885ALDH1A1 3173/4885MAPT 4637/4885 |
| US-20130108685-A1 | CATIONIC LIPID | LPAR3, ACOX3, H1-3 | MGLL 80/4885ALDH1A1 3173/4885MAPT 4637/4885 |
| US-20130280305-A1 | CATIONIC LIPID | LPAR3, ACOX3, H1-3 | MGLL 80/4885ALDH1A1 3173/4885MAPT 4637/4885 |
| US-20150343062-A1 | CATIONIC LIPID | ACOX3, LPAR3, ELOVL3 | MGLL 96/4885ALDH1A1 2926/4885MAPT 4596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.