Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TPMT | P51580 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1490644 | 0.85 | SLC22A12 (0.38) | HPGDMAPTTGM2LCKFYN | |
| SCHEMBL5243236 | 0.75 | HSD17B10 (0.73) | HSD17B10HPGDMAPTTPMTTSHR | |
| SCHEMBL1490631 | 0.74 | NPC1 (0.47) | HSD17B10HPGDMAPTTSHRHTT | |
| SCHEMBL1490951 | 0.74 | MAPT (0.55) | MAPTHTTTUBB1POLB | |
| SCHEMBL30745030 | 0.74 | HSD17B10 (0.51) | HSD17B10HPGDMAPTTPMTTSHR | |
| SCHEMBL5240714 | 0.74 | HSD17B10 (0.51) | HSD17B10HPGDMAPTTPMTTSHR | |
| SCHEMBL5243855 | 0.74 | TSHR (0.53) | HSD17B10HPGDMAPTTPMTTSHR | |
| SCHEMBL1490910 | 0.69 | CES2 (0.52) | HSD17B10HPGDMAPTTGM2CA2 | |
| SCHEMBL20570499 | 0.69 | HSD17B10 (0.46) | HSD17B10HPGDMAPTTPMTTSHR | |
| SCHEMBL28783574 | 0.68 | TSHR (0.43) | HSD17B10TSHRAPOBEC3AHTTAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2477698-A2 | COMPOUNDS USEFUL AGAINST KINETOPLASTIDEAE PARASITES | Centre National de la Recherche Scientifique (FR) | 2012-07-25 | — | — | EP | disclosed |
| WO-2011033115-A2 | COMPOUNDS USEFUL AGAINST KINETOPLASTIDEAE PARASITES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2011-03-24 | — | — | WO | disclosed |