Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | GPR139 | Q6DWJ6 | 3/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1490854 | 0.83 | L3MBTL1 (0.51) | ROCK2ALDH1A1GAA | |
| SCHEMBL12757128 | 0.75 | NPSR1 (0.59) | ROCK2NPSR1ALDH1A1GAAGPR139 | |
| SCHEMBL1490877 | 0.74 | ALDH1A1 (0.45) | ALDH1A1NR3C1 | |
| SCHEMBL22924510 | 0.73 | NPSR1 (0.62) | ROCK2NPSR1ALDH1A1GAAGPR139 | |
| SCHEMBL8593124 | 0.72 | NPSR1 (0.69) | ROCK2NPSR1ALDH1A1GAAMAOB | |
| SCHEMBL14507863 | 0.71 | ALDH1A1 (0.69) | NPSR1ALDH1A1GAA | |
| SCHEMBL1490804 | 0.70 | NPSR1 (0.48) | ROCK2NPSR1ALDH1A1GAAMAOB | |
| SCHEMBL23475921 | 0.70 | NPSR1 (0.54) | ROCK2NPSR1ALDH1A1GAAMAOB | |
| SCHEMBL7221078 | 0.69 | NPSR1 (0.59) | ROCK2NPSR1ALDH1A1GAAMAOB | |
| SCHEMBL13209252 | 0.68 | KAT6A (0.58) | ALDH1A1GAAKAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897609-B2 | Aryl substituted imidazonaphthyridines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-03-01 | — | — | US | disclosed |