Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1490807 | 0.83 | ROCK2 (0.50) | ALDH1A1ROCK2GAA | |
| SCHEMBL30277616 | 0.76 | TP53BP1 (0.67) | L3MBTL1ALDH1A1POLBSMN1; SMN2KMT2A | |
| SCHEMBL104557 | 0.76 | TP53BP1 (0.67) | L3MBTL1ALDH1A1POLBSMN1; SMN2KMT2A | |
| SCHEMBL12829992 | 0.75 | L3MBTL1 (0.63) | L3MBTL1ALDH1A1POLBSMN1; SMN2KMT2A | |
| SCHEMBL13763531 | 0.74 | L3MBTL1 (0.80) | L3MBTL1ALDH1A1POLBSMN1; SMN2KMT2A | |
| SCHEMBL6358306 | 0.72 | ALDH1A1 (0.66) | L3MBTL1ALDH1A1POLBSMN1; SMN2KMT2A | |
| SCHEMBL1490877 | 0.72 | ALDH1A1 (0.45) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL1490852 | 0.71 | L3MBTL1 (0.57) | L3MBTL1ALDH1A1POLBSMN1; SMN2KMT2A | |
| SCHEMBL7214340 | 0.70 | L3MBTL1 (0.69) | L3MBTL1ALDH1A1POLBSMN1; SMN2KMT2A | |
| SCHEMBL104559 | 0.69 | TP53BP1 (0.61) | L3MBTL1SMN1; SMN2KMT2AMEN1TP53BP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897609-B2 | Aryl substituted imidazonaphthyridines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-03-01 | — | — | US | disclosed |