Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 7/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL5032083 | 0.98 | MEN1 (0.41) | MEN1HSP90AA1KMT2ASMN1; SMN2PABPC1 | |
| Bicarbonate SCHEMBL23698434 | 0.94 | MEN1 (0.44) | MEN1HSP90AA1KMT2ASMN1; SMN2 | |
| Bicarbonate SCHEMBL6265469 | 0.94 | MEN1 (0.44) | MEN1HSP90AA1KMT2ASMN1; SMN2 | |
| Acetic Acid SCHEMBL35015 | 0.93 | MEN1 (0.43) | MEN1HSP90AA1KMT2ASMN1; SMN2PABPC1 | |
| Bicarbonate SCHEMBL2127090 | 0.93 | MEN1 (0.40) | MEN1HSP90AA1KMT2ASMN1; SMN2PABPC1 | |
| Bicarbonate SCHEMBL28733245 | 0.92 | MEN1 (0.46) | MEN1HSP90AA1KMT2ASMN1; SMN2 | |
| Propionic Acid SCHEMBL358643 | 0.92 | MEN1 (0.39) | MEN1HSP90AA1KMT2ASMN1; SMN2PABPC1 | |
| Bicarbonate SCHEMBL28939212 | 0.92 | MEN1 (0.46) | MEN1HSP90AA1KMT2ASMN1; SMN2 | |
| Glycolic Acid SCHEMBL18575074 | 0.90 | MEN1 (0.38) | MEN1HSP90AA1KMT2ASMN1; SMN2PABPC1 | |
| Succinic Acid SCHEMBL18575091 | 0.90 | CA1 (0.40) | MEN1HSP90AA1KMT2ASMN1; SMN2PABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111117594-A | Electrochromic material based on dynamic metal-ligand complexation and electrochromic device | 吉林大学 | 2020-05-08 | — | — | CN | claimed |
| US-9394388-B2 | Hybrid supported metallocene catalyst, method for preparing the same, and process for preparing polyolefin using the same | SK INNOVATION CO., LTD. (KR) | 2016-07-19 | — | — | US | claimed |
| US-20150025204-A1 | Hybrid Supported Metallocene Catalyst, Method for Preparing the Same, and Process for Preparing Polyolefin Using the Same | SK INNOVATION CO., LTD. (KR) | 2015-01-22 | — | — | US | claimed |
| WO-2013133595-A1 | HYBRID SUPPORTED METALLOCENE CATALYST, METHOD FOR PREPARING THE SAME, AND PROCESS FOR PREPARING POLYOLEFIN USING THE SAME | SK INNOVATION CO., LTD. (KR) | 2013-09-12 | — | — | WO | claimed |
| US-12291506-B2 | Method for producing amidate compound, and amidate compound | KOEI CHEMICAL COMPANY, LIMITED (JP) | 2025-05-06 | — | — | US | disclosed |
| CN-115074109-A | Electrochromic material and device | 吉林大学 | 2022-09-20 | — | — | CN | disclosed |
| EP-3512905-B1 | METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) | BASF SE (DE) | 2022-08-24 | — | — | EP | disclosed |
| CN-107710462-B | Electrochemical hydrogen storage electrode and battery | 巴斯夫公司 | 2022-08-02 | — | — | CN | disclosed |
| US-20220048864-A1 | METHOD FOR PRODUCING AMIDATE COMPOUND, AND AMIDATE COMPOUND | KOEI CHEMICAL COMPANY, LIMITED (JP) | 2022-02-17 | — | — | US | disclosed |
| CN-107615556-B | Electrolyte and metal hydride battery | 巴斯夫公司 | 2021-11-02 | — | — | CN | disclosed |
| EP-3858817-A1 | METHOD FOR PRODUCING AMIDATE COMPOUND, AND AMIDATE COMPOUND | Koei Chemical Company, Limited (JP) | 2021-08-04 | — | — | EP | disclosed |
| CN-111117594-A | Electrochromic material based on dynamic metal-ligand complexation and electrochromic device | 吉林大学 | 2020-05-08 | — | — | CN | disclosed |
| EP-2515827-A2 | CURABLE DENTAL COMPOSITIONS AND ARTICLES COMPRISING POLYMERIZABLE IONIC LIQUIDS | 3M Innovative Properties Company (US) | 2012-10-31 | — | — | EP | disclosed |
| EP-2470509-A2 | COMPOSITIONS AND ARTICLES COMPRISING POLYMERIZABLE IONIC LIQUID MIXTURE, AND METHODS OF CURING | 3M Innovative Properties Company (US) | 2012-07-04 | — | — | EP | disclosed |
| WO-2012078783-A2 | IMMOBILIZATION OF IONIC LIQUIDS VIA MECHNOCHEMICAL INTERCALATION IN LAYERED MATERIALS | TEXAS STATE UNIVERSITY-SAN MARCOS (US) | 2012-06-14 | — | — | WO | disclosed |
| US-20120101184-A1 | COMPOSITIONS AND ARTICLES COMPRISING POLYMERIZABLE IONIC LIQUID MIXTURE, AND METHODS OF CURING | 3M INNOVATIVE PROPERTIES COMPANY | 2012-04-26 | — | — | US | disclosed |
| WO-2011091131-A2 | ESLICARBAZEPINE ACETATE AND ITS POLYMORPHS | DR. REDDY'S LABORATORIES LTD. (IN) | 2011-07-28 | — | — | WO | disclosed |
| WO-2011087621-A2 | CURABLE DENTAL COMPOSITIONS AND ARTICLES COMPRISING POLYMERIZABLE IONIC LIQUIDS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-07-21 | — | — | WO | disclosed |
| WO-2011025847-A2 | COMPOSITIONS AND ARTICLES COMPRISING POLYMERIZABLE IONIC LIQUID MIXTURE, AND METHODS OF CURING | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-03-03 | — | — | WO | disclosed |
| US-20100213402-A1 | ELECTROLYTE COMPOSITION AND IONIC LIQUID | KANEKA CORPORATION (JP) | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101184-A1 | COMPOSITIONS AND ARTICLES COMPRISING POLYMERIZABLE IONIC LIQUID MIXTURE, AND METHODS OF CURING | ELOVL3, ELOVL6, ELOVL1 | MEN1 2260/4885HSP90AA1 4725/4885KMT2A 3855/4885 |
| US-12291506-B2 | Method for producing amidate compound, and amidate compound | NAAA, NIT2, PAM | MEN1 55/4885HSP90AA1 4241/4885KMT2A 4207/4885 |
| US-20220048864-A1 | METHOD FOR PRODUCING AMIDATE COMPOUND, AND AMIDATE COMPOUND | NAAA, NIT2, PAM | MEN1 55/4885HSP90AA1 4241/4885KMT2A 4207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.