SCHEMBL14910046

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11880041	0.80	MAPK1 (0.42)	MAPK1ALDH1A1TAAR1ALOX15ESR1
	SCHEMBL28706854	0.76	CYP2C19 (0.50)	MAPK1ALDH1A1TSHRMAOBCYP2C19
	SCHEMBL512987	0.76	ALDH1A1 (0.41)	MAPK1ALDH1A1TSHRMAOBCYP2A6
	SCHEMBL2782027	0.74	ALDH1A1 (0.39)	MAPK1ALDH1A1TAAR1KCNN4TSHR
	SCHEMBL4450792	0.72	MAPK1 (0.44)	MAPK1ALDH1A1TAAR1ALOX15ESR1
	SCHEMBL28901983	0.72	ALDH1A1 (0.38)	MAPK1ALDH1A1TAAR1KCNN4TSHR
	SCHEMBL6130600	0.72	CYP2C19 (0.41)	ALDH1A1ALOX15MAPTTSHRMAOB
	SCHEMBL3032334	0.72	ALDH1A1 (0.43)	MAPK1ALDH1A1TSHRMAOBCYP2A6
	SCHEMBL2121346	0.72	ESR1 (0.44)	MAPK1ALDH1A1TAAR1ALOX15ESR1
	SCHEMBL28563681	0.72	ALDH1A1 (0.46)	MAPK1ALDH1A1TAAR1ALOX15ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.