Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 1.00 |
| ▸ | PKM | P14618 | 1/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL568868 | 0.82 | KDM4E (0.72) | ALDH1A1PKMKDM4EP2RX7 | |
| SCHEMBL22516943 | 0.79 | ALDH1A1 (0.66) | ALDH1A1PKMCHRNB2CHRNA4CYP11B1 | |
| SCHEMBL6760429 | 0.79 | KDM4E (0.81) | ALDH1A1PKMKDM4ECYP11B1P2RX7 | |
| SCHEMBL1491110 | 0.78 | KDM4E (1.00) | ALDH1A1PKMKDM4ECYP11B1P2RX7 | |
| SCHEMBL13989341 | 0.78 | ALDH1A1 (0.64) | ALDH1A1PKMCHRNB2CHRNA4CYP11B1 | |
| SCHEMBL14480143 | 0.76 | ALDH1A1 (0.61) | ALDH1A1PKMCHRNB2CHRNA4CYP11B1 | |
| SCHEMBL27514958 | 0.76 | ALDH1A1 (0.61) | ALDH1A1PKMKDM4ECHRNB2CHRNA4 | |
| SCHEMBL17076874 | 0.76 | ALDH1A1 (0.60) | ALDH1A1PKMCHRNB2CHRNA4CYP11B1 | |
| SCHEMBL14221993 | 0.74 | ALDH1A1 (0.59) | ALDH1A1PKMCHRNB2CHRNA4P2RX7 | |
| SCHEMBL16832377 | 0.74 | KDM4E (0.69) | ALDH1A1PKMKDM4ECHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11312722-B2 | Hsp90 inhibitors and uses thereof | TRUSTEES OF BOSTON UNIVERSITY (US) | 2022-04-26 | — | — | US | disclosed |
| US-20200354373-A1 | HSP90 INHIBITORS AND USES THEREOF | TRUSTEES OF BOSTON UNIVERSITY (US) | 2020-11-12 | — | — | US | disclosed |
| WO-2020227368-A1 | HSP90 INHIBITORS AND USES THEREOF | TRUSTEES OF BOSTON UNIVERSITY (US) | 2020-11-12 | — | — | WO | disclosed |
| WO-2014202152-A1 | NEW COSMETIC COMPOSITIONS COMPRISING CATIONIC DYES AND PROCESS FOR DIRECT DYEING OF KERATIN FIBERS | ALFA PARF GROUP S.P.A. (IT) | 2014-12-24 | — | — | WO | disclosed |
| WO-2014202150-A1 | NEW CATIONIC DYES, KITS AND COMPOSITIONS THEREOF, AND PROCESS FOR DYEING KERATIN FIBERS | ALFA PARF GROUP S.P.A. (IT) | 2014-12-24 | — | — | WO | disclosed |
| WO-2014202150-A1 | NEW CATIONIC DYES, KITS AND COMPOSITIONS THEREOF, AND PROCESS FOR DYEING KERATIN FIBERS | ALFA PARF GROUP S.P.A. (IT) | 2014-12-24 | — | — | WO | disclosed |
| WO-2014202152-A1 | NEW COSMETIC COMPOSITIONS COMPRISING CATIONIC DYES AND PROCESS FOR DIRECT DYEING OF KERATIN FIBERS | ALFA PARF GROUP S.P.A. (IT) | 2014-12-24 | — | — | WO | disclosed |
| US-20110086889-A1 | TETRAZOLE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-04-14 | — | — | US | disclosed |
| EP-2288603-A1 | TETRAZOLE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS | Actelion Pharmaceuticals Ltd. (CH) | 2011-03-02 | — | — | EP | disclosed |
| WO-2009150614-A1 | TETRAZOLE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2009-12-17 | — | — | WO | disclosed |
| US-7462204-B2 | Cationic diaminopyrazoles, a process for producing them and colorants containing these compounds | WELLA AG (DE) | 2008-12-09 | — | — | US | disclosed |
| US-20070056120-A1 | Cationic diaminopyrazoles, a process for producing them and colorants containing these compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2007-03-15 | — | — | US | disclosed |
| EP-1687280-A1 | CATIONIC DIAMINOPYRAZOLES, A METHOD FOR THE PRODUCTION THEREOF AND DYES CONTAINING THESE COMPOUNDS | Wella Aktiengesellschaft (DE) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005051918-A1 | CATIONIC DIAMINOPYRAZOLES, A METHOD FOR THE PRODUCTION THEREOF AND DYES CONTAINING THESE COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2005-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200354373-A1 | HSP90 INHIBITORS AND USES THEREOF | HSP90AB1, HSP90B1, HSP90AA1 | ALDH1A1 2482/4885PKM 3236/4885KDM4E 1421/4885 |
| US-20110086889-A1 | TETRAZOLE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS | HCRTR2, HCRTR1, NPY1R | ALDH1A1 3233/4885PKM 2177/4885KDM4E 2955/4885 |
| US-20070056120-A1 | Cationic diaminopyrazoles, a process for producing them and colorants containing these compounds | KRT18, DSP, TUBA4A | ALDH1A1 978/4885PKM 463/4885KDM4E 534/4885 |
| US-11312722-B2 | Hsp90 inhibitors and uses thereof | HSP90AB1, HSP90B1, HSP90AA1 | ALDH1A1 2482/4885PKM 3236/4885KDM4E 1421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.