Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAD51 | Q06609 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 4/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | TNKS | O95271 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1491376 | 0.84 | ENPP2 (0.41) | ENPP2FGFR1ALDH1A1KDM4EHPGD | |
| SCHEMBL7818433 | 0.78 | FGFR1 (0.38) | ENPP2FGFR1ALDH1A1KDM4EHPGD | |
| SCHEMBL16863946 | 0.69 | PKM (0.58) | ENPP2FGFR1ALDH1A1KDM4EHPGD | |
| SCHEMBL7815237 | 0.67 | ESR1 (0.37) | ENPP2ALDH1A1KDM4EHPGDESR1 | |
| SCHEMBL17265930 | 0.65 | FGFR1 (0.56) | ENPP2FGFR1ALDH1A1KDM4EHPGD | |
| SCHEMBL7375589 | 0.65 | ENPP2 (0.42) | ENPP2ALDH1A1KDM4EHPGDESR1 | |
| SCHEMBL29913593 | 0.61 | POLB (0.55) | ENPP2ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL3125096 | 0.61 | CA2 (0.39) | ENPP2FGFR1ALDH1A1KDM4EHPGD | |
| SCHEMBL27919360 | 0.61 | POLB (0.55) | ENPP2ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL1496402 | 0.60 | FGFR1 (0.54) | FGFR1ALDH1A1KDM4EHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011029832-A1 | NOVEL THIAZOL AND OXAZOL HEPCIDINE ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2011-03-17 | — | — | WO | disclosed |