SCHEMBL14239755

SCHEMBL14239755

NCCCC[C@H](N)C(=O)NCCCOCCOCCOCCCNC(=O)CCOCCOCCOCCOCCOCCC(=O)NCCCOCCOCCOCCCNC(=O)[C@@H](N)CCCCN

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ GNAI3 P08754 1/20 0.55
▸ GNAO1 P09471 1/20 0.55
▸ GNAI1 P63096 1/20 0.55
▸ TLR2 O60603 4/20 0.46
▸ TERT O14746 5/20 0.45
▸ DPP7 Q9UHL4 2/20 0.44
▸ RRM1 P23921 1/20 0.43
▸ CD40 P25942 1/20 0.43
▸ CA2 P00918 1/20 0.42
▸ NOS1 P29475 1/20 0.40
▸ MMP2 P08253 1/20 0.40
▸ GSR P00390 1/20 0.39
▸ CHRNA1 P02708 2/20 0.39
▸ CHRNG P07510 2/20 0.39
▸ CHRNB1 P11230 2/20 0.39
▸ CHRND Q07001 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18653794 1.00 GNAI3 (0.55) GNAI3GNAO1GNAI1TLR2TERT
SCHEMBL14916812 1.00 GNAI3 (0.55) GNAI3GNAO1GNAI1TLR2TERT
SCHEMBL20272608 0.99 GNAI3 (0.57) GNAI3GNAO1GNAI1TLR2TERT
SCHEMBL20706553 0.99 GNAI3 (0.57) GNAI3GNAO1GNAI1TLR2TERT
SCHEMBL14240716 0.96 GNAI3 (0.51) GNAI3GNAO1GNAI1TLR2TERT
SCHEMBL14240586 0.95 GNAI3 (0.50) GNAI3GNAO1GNAI1TLR2TERT
SCHEMBL14616413 0.94 GNAI3 (0.59) GNAI3GNAO1GNAI1TLR2TERT
SCHEMBL14616462 0.94 GNAI3 (0.59) GNAI3GNAO1GNAI1TLR2TERT
SCHEMBL14616485 0.94 GNAI3 (0.52) GNAI3GNAO1GNAI1TLR2TERT
SCHEMBL14616412 0.94 GNAI3 (0.52) GNAI3GNAO1GNAI1TLR2TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4171577-B1 PROCESS FOR SYNTHESIZING TARGETING MOLECULES BRISTOL MYERS SQUIBB CO (US) 2026-02-18 — — EP disclosed
US-12522561-B2 Process for synthesizing cationic lipids BRISTOL-MYERS SQUIBB COMPANY (US) 2026-01-13 — — US disclosed
US-20230265050-A1 PROCESS FOR SYNTHESIZING CATIONIC LIPIDS BRISTOL-MYERS SQUIBB COMPANY 2023-08-24 — — US disclosed
US-20230250053-A1 PROCESS FOR SYNTHESIZING TARGETING MOLECULES BRISTOL-MYERS SQUIBB COMPANY 2023-08-10 — — US disclosed
EP-4171577-A1 PROCESS FOR SYNTHESIZING TARGETING MOLECULES Bristol-Myers Squibb Company (US) 2023-05-03 — — EP disclosed
US-10669229-B2 Compounds for targeting drug delivery and enhancing siRNA activity NITTO DENKO CORPORATION (JP) 2020-06-02 — — US disclosed
US-10669229-B2 Compounds for targeting drug delivery and enhancing siRNA activity NITTO DENKO CORPORATION (JP) 2020-06-02 — — US disclosed
EP-2998289-B1 COMPOUNDS FOR TARGETING DRUG DELIVERY AND ENHANCING SIRNA ACTIVITY NITTO DENKO CORP (JP) 2019-08-07 — — EP disclosed
EP-2998289-B1 COMPOUNDS FOR TARGETING DRUG DELIVERY AND ENHANCING SIRNA ACTIVITY NITTO DENKO CORP (JP) 2019-08-07 — — EP disclosed
US-10196637-B2 Retinoid-lipid drug carrier NITTO DENKO CORPORATION (JP) 2019-02-05 — — US disclosed
US-20130210744-A1 TARGETING AGENT FOR CANCER CELL OR CANCER-ASSOCIATED FIBROBLAST NITTO DENKO CORPORATION (JP) 2013-08-15 — — US disclosed
US-20130171240-A1 DRUG CARRIER AND DRUG CARRIER KIT FOR INHIBITING FIBROSIS NITTO DENKO CORPORATION (JP) 2013-07-04 — — US disclosed
US-20130171240-A1 DRUG CARRIER AND DRUG CARRIER KIT FOR INHIBITING FIBROSIS NITTO DENKO CORPORATION (JP) 2013-07-04 — — US disclosed
US-20130171240-A1 DRUG CARRIER AND DRUG CARRIER KIT FOR INHIBITING FIBROSIS NITTO DENKO CORPORATION (JP) 2013-07-04 — — US disclosed
US-20130171127-A1 COMPOSITION FOR REGENERATING NORMAL TISSUE FROM FIBROTIC TISSUE NITTO DENKO CORPORATION (JP) 2013-07-04 — — US disclosed
US-20130171127-A1 COMPOSITION FOR REGENERATING NORMAL TISSUE FROM FIBROTIC TISSUE NITTO DENKO CORPORATION (JP) 2013-07-04 — — US disclosed
US-20130171127-A1 COMPOSITION FOR REGENERATING NORMAL TISSUE FROM FIBROTIC TISSUE NITTO DENKO CORPORATION (JP) 2013-07-04 — — US disclosed
WO-2012170952-A9 COMPOUNDS FOR TARGETING DRUG DELIVERY AND ENHANCING SIRNA ACTIVITY NITTO DENKO CORPORATION (JP) 2013-02-21 — — WO disclosed
US-20130017249-A1 COMPOUNDS FOR TARGETING DRUG DELIVERY AND ENHANCING siRNA ACTIVITY NITTO DENKO CORPORATION (JP) 2013-01-17 — — US disclosed
WO-2012170952-A2 COMPOUNDS FOR TARGETING DRUG DELIVERY AND ENHANCING SIRNA ACTIVITY NITTO DENKO CORPORATION (JP) 2012-12-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130171240-A1 DRUG CARRIER AND DRUG CARRIER KIT FOR INHIBITING FIBROSIS KIT, STRA6, HAVCR2 GNAI3 2230/4885GNAO1 1687/4885GNAI1 1803/4885
US-20230265050-A1 PROCESS FOR SYNTHESIZING CATIONIC LIPIDS PLIN1, FABP4, PLIN3 GNAI3 2327/4885GNAO1 3410/4885GNAI1 1438/4885
US-20130017249-A1 COMPOUNDS FOR TARGETING DRUG DELIVERY AND ENHANCING siRNA ACTIVITY LDLR, RARG, FABP4 GNAI3 3017/4885GNAO1 3483/4885GNAI1 2976/4885
US-20130171127-A1 COMPOSITION FOR REGENERATING NORMAL TISSUE FROM FIBROTIC TISSUE COL1A1, COL2A1, COL14A1 GNAI3 3045/4885GNAO1 3787/4885GNAI1 2852/4885
US-20230250053-A1 PROCESS FOR SYNTHESIZING TARGETING MOLECULES RARG, RARA, RARB GNAI3 1747/4885GNAO1 2144/4885GNAI1 1147/4885
US-10669229-B2 Compounds for targeting drug delivery and enhancing siRNA activity LDLR, RARG, FABP4 GNAI3 3017/4885GNAO1 3483/4885GNAI1 2976/4885
US-20130210744-A1 TARGETING AGENT FOR CANCER CELL OR CANCER-ASSOCIATED FIBROBLAST FGFR2, FRS2, FOLR1 GNAI3 1556/4885GNAO1 2122/4885GNAI1 1632/4885
US-10196637-B2 Retinoid-lipid drug carrier RXRA, RXRG, LRAT GNAI3 3028/4885GNAO1 3716/4885GNAI1 3168/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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