Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 1/20 | 0.48 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.48 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL9617899 | 0.90 | TDP1 (0.50) | TDP1LMNATHRBBLMKMT2A | |
| Glycolic Acid SCHEMBL4565840 | 0.88 | TDP1 (0.45) | TDP1LMNATHRBBLMKMT2A | |
| Propionic Acid SCHEMBL27996411 | 0.88 | FFAR3 (0.46) | TDP1LMNATHRBBLMKMT2A | |
| Acetic Acid SCHEMBL3260807 | 0.88 | TDP1 (0.48) | TDP1LMNATHRBBLMKMT2A | |
| Oxalic Acid SCHEMBL5863172 | 0.88 | TDP1 (0.48) | TDP1LMNATHRBBLMKMT2A | |
| Carbamic Acid SCHEMBL15212189 | 0.88 | TDP1 (0.48) | TDP1LMNATHRBBLMKMT2A | |
| Adipic Acid SCHEMBL1006656 | 0.86 | NFKB1 (0.62) | LMNATHRBBLMKMT2ANPSR1 | |
| Glycine SCHEMBL14742258 | 0.86 | GLRA1 (0.48) | GLRA1SLC6A9OR51E2TDP1TSHR | |
| Urea SCHEMBL2672240 | 0.85 | TDP1 (0.50) | TDP1LMNATHRBBLMKMT2A | |
| Adipic Acid SCHEMBL9065306 | 0.85 | BLM (0.64) | LMNATHRBBLMKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4728447-A1 | ENVIRONMENTAL ATTRIBUTES FOR AROMA CHEMICAL | BASF SE (DE) | 2026-04-22 | — | — | EP | disclosed |
| EP-4366690-B1 | POLYOL ESTER MIXTURE FOR USE AS VASELINE SUBSTITUTE | BASF SE (DE) | 2025-06-25 | — | — | EP | disclosed |
| US-20250017838-A1 | Agent for Oxidatively Dyeing Keratin Fibers | HENKEL AG & CO. KGAA (DE) | 2025-01-16 | — | — | US | disclosed |
| WO-2024260908-A1 | ENVIRONMENTAL ATTRIBUTES FOR AROMA CHEMICAL | BASF SE (DE) | 2024-12-26 | — | — | WO | disclosed |
| US-20240325268-A1 | POLYOL ESTER MIXTURE FOR USE AS VASELINE SUBSTITUTE | BASF SE (DE) | 2024-10-03 | — | — | US | disclosed |
| EP-4366690-A1 | POLYOL ESTER MIXTURE FOR USE AS VASELINE SUBSTITUTE | BASF SE (DE) | 2024-05-15 | — | — | EP | disclosed |
| US-20230398057-A1 | AGENT FOR DYEING KERATINUOS MATERIAL, COMPRISING AMINOSILICONE, A CHROMOPHORIC COMPOUND AND AN ADDITION PRODUCT OF C1-C6 ALKYLENE OXIDE(S) TO THE ESTERS OF FATTY ACIDS AND AROMATIC ALCOHOLS | HENKEL AG & CO. KGAA (DE) | 2023-12-14 | — | — | US | disclosed |
| WO-2023280694-A1 | POLYOL ESTER MIXTURE FOR USE AS VASELINE SUBSTITUTE | BASF SE (DE) | 2023-01-12 | — | — | WO | disclosed |
| EP-4115873-A1 | POLYOL ESTER MIXTURE FOR USE AS VASELINE SUBSTITUTE | BASF SE (DE) | 2023-01-11 | — | — | EP | disclosed |
| EP-3523350-B1 | ULTRAVIOLET RADIATION ABSORBING POLYMER COMPOSITION | BASF SE (DE) | 2022-12-07 | — | — | EP | disclosed |
| CN-1203625-A | Synthetic detergent soap | HENKEL KGAA (DE) | 1998-12-30 | — | — | CN | disclosed |
| US-5840943-A | ESTERIFYING A POLYHYDROXYSTEARIC ACID HAVING A DEGREE OF SELF-CONDENSATION OF FROM 2 TO 20 WITH POLYGLYCEROL COMPONENT; EMULSIFIERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1998-11-24 | — | — | US | disclosed |
| US-5795978-A | CONTAINING ALKYL OR ALKENL OLIGOGLYCOSIDE AND FATTY ALCOHOL;COSMETICS, DRUGS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1998-08-18 | — | — | US | disclosed |
| EP-0844867-A1 | COSMETIC PREPARATIONS CONTAINING ACYL LACTYLATES, PROTEIN HYDROLYSATES AND PROTEIN FATTY ACID CONDENSATES | Henkel Kommanditgesellschaft auf Aktien (DE) | 1998-06-03 | — | — | EP | disclosed |
| US-5716418-A | OXIDATION HAIR COLOR DYES; NONTOXIC, COLORFASTNESS, ABSORPTION, RECEPTIVITY | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1998-02-10 | — | — | US | disclosed |
| CN-1162915-A | Oxidation dyes | HENKEL KGAA (DE) | 1997-10-22 | — | — | CN | disclosed |
| US-5609650-A | HAIR DYES, OXIDATION WITH ATMOSPHERIC OXYGEN | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN | 1997-03-11 | — | — | US | disclosed |
| WO-1997006780-A1 | COSMETIC PREPARATIONS CONTAINING ACYL LACTYLATES, PROTEIN HYDROLYSATES AND PROTEIN FATTY ACID CONDENSATES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1997-02-27 | — | — | WO | disclosed |
| CN-1086707-A | Agent for treatment of hair | HENKEL KGAA (DE) | 1994-05-18 | — | — | CN | disclosed |
| US-4986983-A | IMPROVING TEXTURE, FEEL AND APPEARANCE | REVLON, INC. (US) | 1991-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240325268-A1 | POLYOL ESTER MIXTURE FOR USE AS VASELINE SUBSTITUTE | FASN, DEGS1, ACSL1 | GLRA1 1426/4885SLC6A9 3826/4885OR51E2 699/4885 |
| US-20230398057-A1 | AGENT FOR DYEING KERATINUOS MATERIAL, COMPRISING AMINOSILICONE, A CHROMOPHORIC COMPOUND AND AN ADDITION PRODUCT OF C1-C6 ALKYLENE OXIDE(S) TO THE ESTERS OF FATTY ACIDS AND AROMATIC ALCOHOLS | KRT18, C1S, FAM83E | GLRA1 4234/4885SLC6A9 4575/4885OR51E2 12/4885 |
| US-20250017838-A1 | Agent for Oxidatively Dyeing Keratin Fibers | KRT18, SQOR, ADH4 | GLRA1 3277/4885SLC6A9 4229/4885OR51E2 340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.