Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Urea SCHEMBL2672240 | 0.92 | TDP1 (0.50) | TDP1ALDH1A1TSHRPAOXCYP2C9 | |
| Bicarbonate SCHEMBL9617899 | 0.92 | TDP1 (0.50) | TDP1ALDH1A1TSHRCYP2C9CYP2C19 | |
| Oxalic Acid SCHEMBL5863172 | 0.90 | TDP1 (0.48) | TDP1ALDH1A1TSHRCYP2C9CYP2C19 | |
| Acetic Acid SCHEMBL3260807 | 0.90 | TDP1 (0.48) | TDP1ALDH1A1TSHRPAOXCYP2C9 | |
| Glycine SCHEMBL149185 | 0.88 | GLRA1 (0.48) | TDP1ALDH1A1TSHRCYP2C9CYP2C19 | |
| Propionic Acid SCHEMBL27996411 | 0.86 | FFAR3 (0.46) | TDP1ALDH1A1TSHRCYP2C9CYP2C19 | |
| Glycolic Acid SCHEMBL4565840 | 0.86 | TDP1 (0.45) | TDP1ALDH1A1TSHRCYP2C9CYP2C19 | |
| Carbamic Acid SCHEMBL5488417 | 0.84 | ACHE (0.39) | TDP1ALDH1A1PAOXCYP2C9CYP2C19 | |
| Maleic Acid SCHEMBL27863762 | 0.84 | TDP1 (0.43) | TDP1ALDH1A1TSHRCYP2C9CYP2C19 | |
| Adipic Acid SCHEMBL1006656 | 0.84 | NFKB1 (0.62) | ALDH1A1TSHRCYP1A2GABRR3GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015184326-A1 | CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS | CERULEAN PHARMA INC. (US) | 2015-12-03 | — | — | WO | disclosed |
| WO-2015057847-A1 | CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS | CERULEAN PHARMA INC. (US) | 2015-04-23 | — | — | WO | disclosed |
| EP-2817345-A1 | CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS | Cerulean Pharma Inc. (US) | 2014-12-31 | — | — | EP | disclosed |
| US-20140037573-A1 | CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS | CERULEAN PHARMA INC (US) | 2014-02-06 | — | — | US | disclosed |
| WO-2013126564-A1 | CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS | CERULEAN PHARMA INC. (US) | 2013-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140037573-A1 | CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS | SYNCRIP, EXOSC5, EXOSC9 | TDP1 567/4885ALDH1A1 3222/4885TSHR 2594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.