Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 9/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14918896 | 0.89 | MEN1 (0.41) | MEN1KMT2ATDP1LMNAHTT | |
| SCHEMBL14918747 | 0.87 | HDAC6 (0.48) | MEN1KMT2ALMNAHTTHDAC4 | |
| SCHEMBL14919176 | 0.86 | PDK1 (0.45) | MEN1KMT2ATDP1LMNAHTT | |
| SCHEMBL14919193 | 0.85 | CNR1 (0.46) | MEN1KMT2ADGAT1ALDH1A1HDAC4 | |
| SCHEMBL14918741 | 0.84 | CNR1 (0.45) | MEN1KMT2ADGAT1ALDH1A1HDAC4 | |
| SCHEMBL14918740 | 0.84 | CNR1 (0.45) | MEN1KMT2ADGAT1ALDH1A1HDAC4 | |
| SCHEMBL14918753 | 0.84 | CNR1 (0.45) | MEN1KMT2ADGAT1ALDH1A1HDAC4 | |
| SCHEMBL14918418 | 0.83 | RAB9A (0.46) | MEN1KMT2ADGAT1LMNAALDH1A1 | |
| SCHEMBL14918730 | 0.82 | HDAC6 (0.40) | LMNAHTTHDAC4HDAC6HDAC1 | |
| SCHEMBL14918928 | 0.81 | HDAC4 (0.45) | MEN1KMT2ALMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013066836-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2013-05-10 | — | — | WO | claimed |
| US-8871770-B2 | Carboxamide compounds and methods for using the same | MIDCAP FINANCIAL TRUST | 2014-10-28 | — | — | US | disclosed |
| WO-2013066836-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2013-05-10 | — | — | WO | disclosed |