Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.38 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.38 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.38 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14918747 | 0.90 | HDAC6 (0.48) | MEN1KMT2AHTTMAPTL3MBTL1 | |
| SCHEMBL14919176 | 0.89 | PDK1 (0.45) | MEN1KMT2AHTTALDH1A1MAPT | |
| SCHEMBL14918889 | 0.89 | MEN1 (0.38) | MEN1KMT2AHTTALDH1A1MAPT | |
| SCHEMBL14918432 | 0.88 | HDAC8 (0.45) | MEN1KMT2AHTTMAPTHDAC6 | |
| SCHEMBL14918730 | 0.85 | HDAC6 (0.40) | HTTHDAC6HDAC1HDAC8HDAC4 | |
| SCHEMBL14918928 | 0.84 | HDAC4 (0.45) | MEN1KMT2AHTTALDH1A1HDAC6 | |
| SCHEMBL14918455 | 0.84 | HDAC6 (0.51) | MEN1KMT2AALDH1A1L3MBTL1HDAC6 | |
| SCHEMBL14918924 | 0.83 | HDAC1 (0.48) | KMT2AHTTMAPTL3MBTL1HDAC6 | |
| SCHEMBL14918772 | 0.83 | PDK1 (0.44) | MEN1KMT2AALDH1A1HDAC6HDAC1 | |
| SCHEMBL14919134 | 0.82 | HDAC1 (0.50) | MEN1KMT2AALDH1A1MAPTHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013066836-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2013-05-10 | — | — | WO | claimed |