Acetic Acid

Acetic Acid

SCHEMBL4340902

CC(=O)O.OCC(O)CCCCCCCCCCCS.OCCO.OCCO.OCCO.OCCO.OCCO

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ACACB O00763 1/20 0.42
ACACA Q13085 1/20 0.42
FOLH1 Q04609 4/20 0.41
GPR84 Q9NQS5 5/20 0.39
THRB P10828 1/20 0.38
FFAR4 Q5NUL3 1/20 0.38
FFAR1 O14842 1/20 0.38
PTPN1 P18031 1/20 0.36
PSMD14 O00487 2/20 0.34
PLA2G1B P04054 2/20 0.34
MMP2 P08253 2/20 0.34
ATG4B Q9Y4P1 2/20 0.34
HSP90AA1 P07900 1/20 0.34
RAD52 P43351 1/20 0.34
USP2 O75604 1/20 0.33
CYP3A4 P08684 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL18188061 0.88 THRB (0.48) ACACBACACAFOLH1THRBPTPN1
Ethylene Glycol SCHEMBL12493198 0.88 THRB (0.48) ACACBACACAFOLH1THRBPTPN1
Ethylene Glycol SCHEMBL14919937 0.88 THRB (0.48) ACACBACACAFOLH1THRBPTPN1
Ethylene Glycol SCHEMBL2402471 0.88 THRB (0.48) ACACBACACAFOLH1THRBPTPN1
SCHEMBL25211485 0.84 LMNA (0.46) ACACBACACAFOLH1GPR84THRB
SCHEMBL19859887 0.84 LMNA (0.46) ACACBACACAFOLH1GPR84THRB
SCHEMBL25211230 0.84 LMNA (0.46) ACACBACACAFOLH1GPR84THRB
Acetic Acid SCHEMBL6654804 0.82 THRB (0.46) ACACBACACAGPR84THRBFFAR4
SCHEMBL3411530 0.82
Acetic Acid SCHEMBL7070635 0.81 GPR84 (0.46) ACACBACACAFOLH1GPR84FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7598092-B2 Methods, devices, systems and computer program products for stochastic, competitive, force-based analyte detection TOONE ERIC 2009-10-06 US disclosed
WO-2008051314-A2 METHODS, DEVICES, SYSTEMS AND COMPUTER PROGRAM PRODUCTS FOR STOCHASTIC, COMPETITIVE, FORCE-BASED ANALYTE DETECTION DUKE UNIVERSITY (US) 2008-05-02 WO disclosed
US-20080090259-A1 METHODS, DEVICES, SYSTEMS AND COMPUTER PROGRAM PRODUCTS FOR STOCHASTIC, COMPETITIVE, FORCE-BASED ANALYTE DETECTION TOONE ERIC 2008-04-17 US disclosed