Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 16/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 15/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14935005 | 0.83 | SLC6A3 (0.38) | SLC6A3SLC6A4SLC6A2MAOAMAOB | |
| SCHEMBL16197589 | 0.77 | SLC6A4 (0.34) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL14920148 | 0.76 | ALDH1A1 (0.45) | PLAUSLC6A3SLC6A4HTTKMT2A | |
| SCHEMBL27020188 | 0.74 | PLAU (0.39) | PLAUHTTKMT2A | |
| SCHEMBL23580162 | 0.71 | PLAU (0.40) | PLAUHTTKMT2A | |
| SCHEMBL14920534 | 0.71 | PLAU (0.44) | PLAUHTTKMT2A | |
| SCHEMBL14920377 | 0.70 | SLC6A4 (0.34) | SLC6A3SLC6A4 | |
| SCHEMBL16000810 | 0.70 | PLAU (0.39) | PLAUHTTKMT2A | |
| SCHEMBL16000809 | 0.70 | PLAU (0.36) | PLAUHTTKMT2A | |
| SCHEMBL14919923 | 0.70 | PLAU (0.36) | PLAUHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773617-B1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-08-22 | — | — | EP | disclosed |
| US-10029986-B2 | Alkynyl pyridine-substituted amide compound and pesticide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2018-07-24 | — | — | US | disclosed |
| US-20170008847-A1 | ALKYNYL PYRIDINE-SUBSTITUTED AMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-01-12 | — | — | US | disclosed |
| EP-3109234-A1 | ALKYNYLPYRIDINE-SUBSTITUTED AMIDE COMPOUND AND NOXIOUS ORGANISM CONTROL AGENT | Nissan Chemical Industries, Ltd. (JP) | 2016-12-28 | — | — | EP | disclosed |
| US-20160309717-A1 | Compounds with Nematicidal Activity | BAYER CROPSCIENCE AG (DE) | 2016-10-27 | — | — | US | disclosed |
| US-20160309717-A1 | Compounds with Nematicidal Activity | BAYER CROPSCIENCE AG (DE) | 2016-10-27 | — | — | US | disclosed |
| US-20160309717-A1 | Compounds with Nematicidal Activity | BAYER CROPSCIENCE AG (DE) | 2016-10-27 | — | — | US | disclosed |
| EP-3083585-A1 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | Bayer CropScience Aktiengesellschaft (DE) | 2016-10-26 | — | — | EP | disclosed |
| EP-2773631-B1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-09-09 | — | — | EP | disclosed |
| EP-2773631-B1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-09-09 | — | — | EP | disclosed |
| US-20140296066-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-02 | — | — | US | disclosed |
| US-20140296067-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-02 | — | — | US | disclosed |
| US-20140296067-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-02 | — | — | US | disclosed |
| US-20140296067-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-02 | — | — | US | disclosed |
| US-20140296066-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-02 | — | — | US | disclosed |
| US-20140296066-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-02 | — | — | US | disclosed |
| EP-2773617-A1 | PESTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2014-09-10 | — | — | EP | disclosed |
| EP-2773631-A1 | PESTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2014-09-10 | — | — | EP | disclosed |
| WO-2013064521-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-05-10 | — | — | WO | disclosed |
| WO-2013064519-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160309717-A1 | Compounds with Nematicidal Activity | ACHE, NAAA, TUBA3C | PLAU 3522/4885SLC6A3 4434/4885SLC6A4 4212/4885 |
| US-20140296067-A1 | PESTICIDAL COMPOUNDS | C5, CBR3, C3AR1 | PLAU 4123/4885SLC6A3 2297/4885SLC6A4 2108/4885 |
| US-10029986-B2 | Alkynyl pyridine-substituted amide compound and pesticide | CHRM1, CHRM2, CHRM3 | PLAU 4881/4885SLC6A3 1784/4885SLC6A4 3414/4885 |
| US-20140296066-A1 | PESTICIDAL COMPOUNDS | C5, CYC1, ACHE | PLAU 4175/4885SLC6A3 3711/4885SLC6A4 3642/4885 |
| US-20170008847-A1 | ALKYNYL PYRIDINE-SUBSTITUTED AMIDE COMPOUND AND PESTICIDE | CHRM1, CHRM2, CHRM3 | PLAU 4881/4885SLC6A3 1784/4885SLC6A4 3414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.