Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 12/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TLR4 | O00206 | 1/20 | 0.35 |
| ▸ | TLR2 | O60603 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | VCP | P55072 | 1/20 | 0.34 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14920926 | 1.00 | FBP1 (0.45) | FBP1RXRAHSP90AA1ALDH1A1MAPT | |
| SCHEMBL2132111 | 0.78 | PRMT1 (0.43) | FBP1RXRAHSP90AA1ALDH1A1MAPT | |
| SCHEMBL2132119 | 0.78 | PRMT1 (0.43) | FBP1RXRAHSP90AA1ALDH1A1MAPT | |
| SCHEMBL2129117 | 0.78 | ALDH1A1 (0.42) | FBP1RXRAHSP90AA1ALDH1A1MAPT | |
| SCHEMBL2129111 | 0.78 | ALDH1A1 (0.42) | FBP1RXRAHSP90AA1ALDH1A1MAPT | |
| SCHEMBL2130421 | 0.77 | FBP1 (0.41) | FBP1RXRAALDH1A1MAPTLMNA | |
| SCHEMBL2130426 | 0.77 | FBP1 (0.41) | FBP1RXRAALDH1A1MAPTLMNA | |
| SCHEMBL1085828 | 0.76 | ALDH1A1 (0.41) | ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL3783377 | 0.75 | MIF (0.41) | RXRAALDH1A1MAPTLMNAHPGD | |
| SCHEMBL3778055 | 0.75 | MIF (0.41) | RXRAALDH1A1MAPTLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9301526-B2 | Compounds with nematicidal activity | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-04-05 | — | — | US | disclosed |
| US-9301526-B2 | Compounds with nematicidal activity | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-04-05 | — | — | US | disclosed |
| US-20140256728-A1 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-09-11 | — | — | US | disclosed |
| US-20140256728-A1 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-09-11 | — | — | US | disclosed |
| US-20140256728-A1 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-09-11 | — | — | US | disclosed |
| EP-2773215-A2 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | Bayer Intellectual Property GmbH (DE) | 2014-09-10 | — | — | EP | disclosed |
| EP-2773203-A1 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | Bayer Intellectual Property GmbH (DE) | 2014-09-10 | — | — | EP | disclosed |
| US-20140249149-A1 | Compounds with Nematicidal Activity | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-09-04 | — | — | US | disclosed |
| US-20140249149-A1 | Compounds with Nematicidal Activity | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-09-04 | — | — | US | disclosed |
| WO-2013064461-A2 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-10 | — | — | WO | disclosed |
| WO-2013064461-A2 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-10 | — | — | WO | disclosed |
| WO-2013064460-A1 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-10 | — | — | WO | disclosed |
| WO-2013064460-A1 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256728-A1 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | ACHE, TUBA3C, NAAA | FBP1 2007/4885RXRA 3391/4885HSP90AA1 1937/4885 |
| US-20140249149-A1 | Compounds with Nematicidal Activity | ACHE, NAAA, TUBA3C | FBP1 1314/4885RXRA 2518/4885HSP90AA1 2848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.