Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 5/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TYMS | P04818 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | DPP3 | Q9NY33 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12114036 | 0.85 | MCL1 (0.58) | MCL1KDM4EALDH1A1L3MBTL1MEN1 | |
| SCHEMBL2367407 | 0.80 | MCL1 (1.00) | MCL1KDM4EMAPTALDH1A1TDP1 | |
| SCHEMBL14922764 | 0.75 | MCL1 (0.70) | MCL1KDM4EMAPTPABPC1ALDH1A1 | |
| SCHEMBL16602011 | 0.75 | MCL1 (0.57) | MCL1CYP1A2 | |
| SCHEMBL12114092 | 0.74 | MCL1 (0.51) | MCL1KDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL16602007 | 0.74 | MCL1 (0.56) | MCL1CYP1A2 | |
| SCHEMBL16602008 | 0.73 | MCL1 (0.55) | MCL1MAPTMEN1KMT2A | |
| SCHEMBL15765900 | 0.72 | MCL1 (0.58) | MCL1 | |
| SCHEMBL16602019 | 0.72 | MCL1 (0.53) | MCL1CYP1A2 | |
| SCHEMBL16602012 | 0.71 | MCL1 (0.52) | MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8465889-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2013-06-18 | — | — | US | disclosed |
| US-8435706-B2 | — | — | 2013-05-07 | — | — | US | disclosed |