Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 7/20 | 1.00 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13302003 | 0.84 | MCL1 (0.71) | MCL1MAP1LC3BCA1CA2 | |
| SCHEMBL14922764 | 0.83 | MCL1 (0.70) | MCL1MAP1LC3BCA1CA2ALDH1A1 | |
| SCHEMBL13302002 | 0.81 | MCL1 (0.67) | MCL1MAP1LC3BCA1CA2CYP1A2 | |
| SCHEMBL14922765 | 0.80 | MCL1 (0.67) | MCL1CA1CA2ALDH1A1HPGD | |
| SCHEMBL15229541 | 0.80 | MCL1 (0.67) | MCL1MAP1LC3BCA1CA2ALDH1A1 | |
| SCHEMBL15229667 | 0.80 | MCL1 (0.67) | MCL1MAP1LC3BCA1CA2ALDH1A1 | |
| SCHEMBL13694210 | 0.80 | MCL1 (0.65) | MCL1MAP1LC3BCA1CA2ALDH1A1 | |
| SCHEMBL15243621 | 0.76 | MCL1 (0.60) | MCL1MAP1LC3BCA1CA2ALDH1A1 | |
| SCHEMBL15243620 | 0.76 | MCL1 (0.60) | MCL1MAP1LC3BCA1CA2ALDH1A1 | |
| SCHEMBL15765900 | 0.74 | MCL1 (0.58) | MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117624019-A | Naphthol [1,8-ef ] isoindole-7, 8,10 (9H) -trione derivative and preparation method and application thereof | 华侨大学 | 2024-03-01 | — | — | CN | disclosed |
| US-9182350-B2 | Naphthalene-based two-photon fluorescent probes, preparation method and use thereof | DALIAN UNIVERSITY OF TECHNOLOGY (CN) | 2015-11-10 | — | — | US | disclosed |
| EP-2778161-B1 | TWO-PHOTON FLUORESCENT PROBE USING NAPHTHALENE AS MATRIX AND PREPARATION METHOD AND USE THEREOF | UNIV DALIAN TECH (CN) | 2015-05-06 | — | — | EP | disclosed |
| US-20150079625-A1 | NAPHTHALENE-BASED TWO-PHOTON FLUORESCENT PROBES, PREPARATION METHOD AND USE THEREOF | DALIAN CHROMAS BIOSCIENCE CO., LTD (CN) | 2015-03-19 | — | — | US | disclosed |
| US-20110251188-A1 | ACENAPHTHO HETEROCYCLE COMPOUNDS, CYCLODEXTRIN INCLUSION COMPOUNDS AND COMPLEXES, AND USES IN THE MANUFACTURES OF BH3 PROTEIN ANALOGUE, BCL-2 FAMILY PROTEIN INHIBITORS THEREOF | DALIAN UNIVERSITY OF TECHNOLOGY (CN) | 2011-10-13 | — | — | US | disclosed |
| EP-2366701-A1 | ACENAPHTHO HETEROCYCLE COMPOUNDS, CYCLODEXTRIN INCLUSION COMPOUNDS AND COMPLEXES, AND USES IN THE MANUFACTURES OF BH3 PROTEIN ANALOGUE, BCL-2 FAMILY PROTEIN INHIBITORS THEREOF | Dalian University Of Technology (CN) | 2011-09-21 | — | — | EP | disclosed |
| US-7745083-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2010-06-29 | — | — | US | disclosed |
| US-20090297218-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2009-12-03 | — | — | US | disclosed |
| US-7592113-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2009-09-22 | — | — | US | disclosed |
| US-20080233499-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2008-09-25 | — | — | US | disclosed |
| US-7396622-B2 | Having a charge generation layer containing a phenanthrene compound, a phenanthroline compound or an acenaphthene compound that has two oxo-, phenylimino- or dicyanovinylene groups that may be the same or different; charge-generating material is preferably hydroxygallium phthalocyanine. | CANON KABUSHIKI KAISHA (JP) | 2008-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251188-A1 | ACENAPHTHO HETEROCYCLE COMPOUNDS, CYCLODEXTRIN INCLUSION COMPOUNDS AND COMPLEXES, AND USES IN THE MANUFACTURES OF BH3 PROTEIN ANALOGUE, BCL-2 FAMILY PROTEIN INHIBITORS THEREOF | BID, BCL2, BAX | MCL1 10/4885MAP1LC3B 1133/4885CA1 1581/4885 |
| US-20150079625-A1 | NAPHTHALENE-BASED TWO-PHOTON FLUORESCENT PROBES, PREPARATION METHOD AND USE THEREOF | ANXA4, ANXA3, ANTXR2 | MCL1 1082/4885MAP1LC3B 1947/4885CA1 1354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.