Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 5/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.30 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12113984 | 0.86 | MCL1 (0.53) | MCL1KDM4E | |
| SCHEMBL2367407 | 0.83 | MCL1 (1.00) | MCL1CYP1A2CA1CA2MAP1LC3B | |
| SCHEMBL13302002 | 0.81 | MCL1 (0.67) | MCL1CYP1A2CA1CA2MAP1LC3B | |
| SCHEMBL13302003 | 0.81 | MCL1 (0.71) | MCL1CA1CA2MAP1LC3B | |
| SCHEMBL13694210 | 0.80 | MCL1 (0.65) | MCL1CA1CA2MAP1LC3BKDM4E | |
| SCHEMBL13302005 | 0.77 | MCL1 (0.43) | MCL1 | |
| SCHEMBL14922765 | 0.75 | MCL1 (0.67) | MCL1CYP1A2CYP2A6CA1CA2 | |
| Water SCHEMBL27730349 | 0.70 | CYP1A2 (0.48) | MCL1CYP1A2CYP2A6MAOAKDM4E | |
| SCHEMBL9807294 | 0.70 | CYP1A2 (0.52) | CYP1A2CYP2A6MAOAKDM4EALDH1A1 | |
| SCHEMBL12114036 | 0.69 | MCL1 (0.58) | MCL1KDM4EMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8465889-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2013-06-18 | — | — | US | disclosed |
| US-8435706-B2 | — | — | 2013-05-07 | — | — | US | disclosed |