Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 5/20 | 0.52 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.35 |
| ▸ | WEE1 | P30291 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | CALML3 | P27482 | 1/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | CHUK | O15111 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16602007 | 0.89 | MCL1 (0.56) | MCL1PRKDC | |
| SCHEMBL16602008 | 0.83 | MCL1 (0.55) | MCL1CHEK1WEE1IKBKB | |
| SCHEMBL16602019 | 0.82 | MCL1 (0.53) | MCL1 | |
| SCHEMBL16602004 | 0.81 | MCL1 (0.52) | MCL1ACMSDAKR1C3AKR1C2 | |
| SCHEMBL16602011 | 0.80 | MCL1 (0.57) | MCL1 | |
| SCHEMBL16601994 | 0.77 | MCL1 (0.49) | MCL1CHEK1WEE1 | |
| SCHEMBL16601996 | 0.74 | MCL1 (0.52) | MCL1CHEK1WEE1IKBKB | |
| SCHEMBL16601995 | 0.72 | MCL1 (0.50) | MCL1AKR1C3AKR1C2 | |
| SCHEMBL14922765 | 0.71 | MCL1 (0.67) | MCL1 | |
| SCHEMBL2367407 | 0.70 | MCL1 (1.00) | MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |