Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 5/20 | 0.55 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | WEE1 | P30291 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | PRF1 | P14222 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16601996 | 0.91 | MCL1 (0.52) | MCL1BRD4IKBKBCNR1CNR2 | |
| SCHEMBL16602012 | 0.83 | MCL1 (0.52) | MCL1IKBKBCHEK1WEE1 | |
| SCHEMBL16602004 | 0.83 | MCL1 (0.52) | MCL1TDP2 | |
| SCHEMBL16602011 | 0.80 | MCL1 (0.57) | MCL1 | |
| SCHEMBL16602007 | 0.79 | MCL1 (0.56) | MCL1BRD4PRF1 | |
| SCHEMBL16602019 | 0.77 | MCL1 (0.53) | MCL1 | |
| SCHEMBL16601995 | 0.74 | MCL1 (0.50) | MCL1TDP2 | |
| SCHEMBL14922765 | 0.73 | MCL1 (0.67) | MCL1MAPTMEN1KMT2A | |
| SCHEMBL2367407 | 0.72 | MCL1 (1.00) | MCL1MAPT | |
| SCHEMBL15765900 | 0.70 | MCL1 (0.58) | MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |