Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL9325821 | 0.94 | — | — | |
| Potassium Ion SCHEMBL3178692 | 0.94 | — | — | |
| Lithium Ion SCHEMBL7200656 | 0.89 | — | — | |
| Potassium Ion SCHEMBL15142244 | 0.89 | — | — | |
| Potassium Ion SCHEMBL5864380 | 0.89 | — | — | |
| Potassium Ion SCHEMBL3197808 | 0.89 | — | — | |
| SCHEMBL2402 | 0.88 | — | — | |
| SCHEMBL31745292 | 0.88 | TSHR (0.30) | — | |
| SCHEMBL16970939 | 0.88 | TSHR (0.30) | — | |
| Potassium Ion SCHEMBL41 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2289968-B1 | Polyester process | XEROX CORP (US) | 2016-04-27 | — | — | EP | disclosed |
| US-9306176-B2 | Organic electroluminescent device; a charge transporting material for the organic electroluminescent device; and a luminescent device, a display device and a lighting system using the organic electroluminescent device | UDC IRELAND LIMITED (IE) | 2016-04-05 | — | — | US | disclosed |
| US-20140034914-A1 | Organic Electroluminescent Device; A Charge Transporting Material For The Organic Electroluminescent Device; And A Luminescent Device, A Display Device And A Lighting System Using The Organic Electroluminescent Device | UDC IRELAND LIMITED (IE) | 2014-02-06 | — | — | US | disclosed |
| US-8466254-B2 | Polyester process | XEROX CORPORATION (US) | 2013-06-18 | — | — | US | disclosed |
| US-8410282-B2 | Compounds as adenosine A1 receptor antagonists | PALOBIOFARMA, S.L. (ES) | 2013-04-02 | — | — | US | disclosed |
| US-20120283392-A1 | POLYESTER PROCESS | XEROX CORPORATION (US) | 2012-11-08 | — | — | US | disclosed |
| US-8257899-B2 | Polyester process | XEROX CORPORATION (US) | 2012-09-04 | — | — | US | disclosed |
| EP-2197860-B1 | NEW COMPOUNDS AS ADENOSINE A1 RECEPTOR ANTAGONISTS | PALOBIOFARMA SL (ES) | 2011-05-25 | — | — | EP | disclosed |
| US-20110053079-A1 | POLYESTER PROCESS | XEROX CORPORATION (US) | 2011-03-03 | — | — | US | disclosed |
| EP-2289968-A1 | Polyester process | Xerox Corporation (US) | 2011-03-02 | — | — | EP | disclosed |
| US-20100311703-A1 | NEW COMPOUNDS AS ADENOSINE A1 RECEPTOR ANTAGONISTS | PALOBIOFARMA, S.L. (ES) | 2010-12-09 | — | — | US | disclosed |
| EP-2197860-A1 | NEW COMPOUNDS AS ADENOSINE A1 RECEPTOR ANTAGONISTS | Palobiofarma, S.L. (ES) | 2010-06-23 | — | — | EP | disclosed |
| WO-2009044250-A1 | NEW COMPOUNDS AS ADENOSINE A1 RECEPTOR ANTAGONISTS | PALOBIOFARMA, S.L. (ES) | 2009-04-09 | — | — | WO | disclosed |
| US-6127080-A | TONER COMPRISED OF COLORANT AND POLYESTER FORMED BY REACTING ORGANIC DIOL WITH CYCLIC ALKYLENE CARBONATE IN PRESENCE OF FIRST CATALYST, ADDING FURTHER CARBONATE IN PRESENCE OF SECOND CATALYST, CONDENSING WITH DICARBOXYLIC ACID | XEROX CORPORATION (US) | 2000-10-03 | — | — | US | disclosed |
| US-6063827-A | Polyester process | XEROX CORPORATION (US) | 2000-05-16 | — | — | US | disclosed |
| EP-0974612-A2 | Preparation of unsaturated polyether esters | Xerox Corporation (US) | 2000-01-26 | — | — | EP | disclosed |
| US-5324869-A | Chemical intermediates for sarcophytol a | MITSUBISHI KASEI CORPORATION (JP) | 1994-06-28 | — | — | US | disclosed |
| EP-0155392-A2 | Improved processes for preparing 7-(2-hexyl-5-hydroxy-cyclopentyl)-heptanoic acid | IBI- Istituto Biochimico Italiano Giovanni Lorenzini S.p.A. (IT) | 1985-09-25 | — | — | EP | disclosed |
| US-4386220-A | Polyunsaturated bicyclic compounds, their preparation and use of same as starting materials for preparing monounsaturated bicyclic compounds | FIRMENICH, SA (CH) | 1983-05-31 | — | — | US | disclosed |
| US-4351977-A | Polyunsaturated bicyclic compounds, their preparation and use of same as starting materials for preparing monounsaturated bicyclic compounds | FIRMENICH SA (CH) | 1982-09-28 | — | — | US | disclosed |