Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL3197808 | 0.94 | — | — | |
| Potassium Ion SCHEMBL5864380 | 0.94 | — | — | |
| Potassium Ion SCHEMBL1492527 | 0.94 | — | — | |
| SCHEMBL16970939 | 0.94 | TSHR (0.30) | — | |
| Potassium Ion SCHEMBL14630574 | 0.94 | TSHR (0.30) | — | |
| SCHEMBL31745292 | 0.94 | TSHR (0.30) | — | |
| Potassium Ion SCHEMBL41 | 0.94 | — | — | |
| SCHEMBL2402 | 0.94 | — | — | |
| Ammonia Solution, Strong SCHEMBL545541 | 0.88 | — | — | |
| Potassium Ion SCHEMBL2866209 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250206703-A1 | PROCESS FOR PREPARING ((1S,2S)-2-(5-METHYLPYRIDIN-2-YL)CYCLOPROPYL)METHANOL | MERCK SHARP & DOHME LLC (US) | 2025-06-26 | — | — | US | claimed |
| EP-4504703-A1 | PROCESS FOR PREPARING ((1S,2S)-2-(5-METHYLPYRIDIN-2-YL)CYCLOPROPYL)METHANOL | Merck Sharp & Dohme LLC (US) | 2025-02-12 | — | — | EP | claimed |
| WO-2023192170-A1 | PROCESS FOR PREPARING ((1S,2S)-2-(5-METHYLPYRIDIN-2-YL)CYCLOPROPYL)METHANOL | MERCK SHARP & DOHME LLC (US) | 2023-10-05 | — | — | WO | claimed |
| CN-110498764-A | A kind of synthetic method of doxylamine succinate | SHENZHEN ORIENTAL PHARMACEUTICAL CO LTD | 2019-11-26 | — | — | CN | claimed |
| CN-122011088-A | Cyclic peptide compound and preparation method and application thereof | 甫康生物科技(上海)股份有限公司 | 2026-05-12 | — | — | CN | disclosed |
| EP-4735449-A1 | TETRACYCLIC COMPOUNDS CONTAINING A FUSED INDOLE FOR TREATING APOL1-MEDIATED CHRONIC KIDNEY DISEASE | OmniAB, Inc. (US) | 2026-05-06 | — | — | EP | disclosed |
| US-12421200-B2 | Manganese-catalysed hydrogenation of esters | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2025-09-23 | — | — | US | disclosed |
| CN-120136669-A | Manganese catalyzed ester hydrogenation | 圣安德鲁斯大学董事会 | 2025-06-13 | — | — | CN | disclosed |
| WO-2025006262-A1 | TETRACYCLIC COMPOUNDS CONTAINING A FUSED INDOLE FOR TREATING APOL1-MEDIATED CHRONIC KIDNEY DISEASE | OMNIAB, INC. (US) | 2025-01-02 | — | — | WO | disclosed |
| CN-115385930-B | Preparation method of primani | 药璞(上海)医药科技有限公司 | 2024-04-05 | — | — | CN | disclosed |
| WO-2023190767-A1 | POLYETHER ETHER KETONE DECOMPOSITION METHOD AND NOVEL SUBSTANCE USING STARTING MATERIAL THAT IS DECOMPOSITION PRODUCT OBTAINED BY THIS DECOMPOSITION METHOD | 国立研究開発法人産業技術総合研究所 | 2023-10-05 | — | — | WO | disclosed |
| CN-110498764-B | Synthesis method of doxylamine succinate | 深圳沃兰德药业有限公司 | 2023-09-08 | — | — | CN | disclosed |
| US-20100004447-A1 | PROCESS FOR PREPARATION OF 9-HYDROXY-3-(2-CHLOROETHYL)-2-METHYL-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE HYDROCHLORIDE | ACTAVIS GROUP PTC EHF (IS) | 2010-01-07 | — | — | US | disclosed |
| WO-2008087557-A2 | AN IMPROVED PROCESS FOR PREPARATION OF 9-HYDROXY-3-(2-CHLOROETHYL)- 2-METHYL-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE HYDROCHLORIDE | ACTAVIS GROUP PTC EHF (US) | 2008-07-24 | — | — | WO | disclosed |
| CN-1733692-A | Two-step industrial synthesis method of beta-(3,5-di tertiary butyl-4-hydroxyl phenyl )octadecyl propionate | TIANJIN CHENGUANG CHEMICAL IND (CN) | 2006-02-15 | — | — | CN | disclosed |
| CN-1109676-C | Substituted aminophenyluracils as herbicides and insecticides | BAYER AG (DE) | 2003-05-28 | — | — | CN | disclosed |
| CN-1365353-A | Geometrical isomer of acrylonitrile compounds, mixture thereof, and process for producing these | ISHIHARA SANGYO KAISHA (JP) | 2002-08-21 | — | — | CN | disclosed |
| CN-1189157-A | Substituted aminophenyluracils as herbicides and insecticides | BAYER AG (DE) | 1998-07-29 | — | — | CN | disclosed |
| EP-0448188-A2 | Process and intermediates for the preparation of substituted 6-(3,5,6,7-tetrahydropyrrolo-[2,1-c][1,2,4]-thiadiazol-3-ylidenimino)-7-fluoro-2H-1,4-benzoxazin-3(4H)-ones | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-09-25 | — | — | EP | disclosed |
| US-4981872-A | ANTIULCER | SANKYO COMPANY LIMITED (JP) | 1991-01-01 | — | — | US | disclosed |