SCHEMBL2340285

SCHEMBL2340285

Cc1cccc(C)c1-c1ccc2c(c1)-c1cc(-c3c(C)cccc3C)ccc1C2

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIA1 P42261 4/20 0.50
CACNG8 Q8WXS5 4/20 0.50
SRC P12931 2/20 0.41
HTR7 P34969 2/20 0.41
HRH4 Q9H3N8 1/20 0.38
FFAR1 O14842 1/20 0.37
KDM4E B2RXH2 2/20 0.37
LMNA P02545 2/20 0.37
MAPT P10636 2/20 0.37
NPC1 O15118 1/20 0.37
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.37
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
KMT2A Q03164 1/20 0.36
FYN P06241 1/20 0.36
CLK4 Q9HAZ1 1/20 0.36
DYRK1B Q9Y463 1/20 0.36
BRD4 O60885 1/20 0.36
ADORA1 P30542 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30885502 0.88 GRIA1 (0.54) GRIA1CACNG8SRCHTR7HRH4
SCHEMBL4895870 0.80 GRIA1 (0.53) GRIA1CACNG8HTR7KDM4ELMNA
SCHEMBL14925866 0.78 GRIA1 (0.49) GRIA1CACNG8SRCHTR7ALDH1A1
SCHEMBL22889028 0.73 METAP1 (0.43) KDM4ELMNAMAPTNPC1ALDH1A1
SCHEMBL12565770 0.73 HTR7 (0.53) GRIA1CACNG8SRCHTR7FFAR1
SCHEMBL4895881 0.72 ESR1 (0.42) FYNCLK4DYRK1B
SCHEMBL7939919 0.72 MAPT (0.39) GRIA1CACNG8HTR7KDM4ELMNA
SCHEMBL30704456 0.72 PTPN11 (0.53) GRIA1CACNG8SRCHTR7ALDH1A1
SCHEMBL599052 0.71 MAOA (0.46) KDM4ELMNAMAPTNPC1ALDH1A1
SCHEMBL7938898 0.71 TSHR (0.43) GRIA1CACNG8MAPTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8299459-B2 Diindenopicene compound and organic light emitting device using the same CANON KABUSHIKI KAISHA (JP) 2012-10-30 US disclosed
US-20110204349-A1 DIINDENOPICENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2011-08-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110204349-A1 DIINDENOPICENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME ALDH1A2, CYP46A1, NR2E3 GRIA1 829/4885CACNG8 1558/4885SRC 3829/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.