Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16535500 | 0.92 | TSHR (0.36) | MEN1KMT2ATSHRCTSKPOLB | |
| SCHEMBL14256285 | 0.88 | TDP1 (0.48) | MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL21183917 | 0.86 | FAAH (0.33) | MEN1KMT2ATSHRCTSK | |
| SCHEMBL14256235 | 0.85 | POLB (0.37) | MEN1KMT2ATSHRCTSKTDP1 | |
| SCHEMBL213520 | 0.84 | TSHR (0.45) | MEN1KMT2ATSHRCTSKTDP1 | |
| SCHEMBL14927406 | 0.83 | TSHR (0.36) | MEN1KMT2ATSHRCTSKPOLB | |
| SCHEMBL14927412 | 0.81 | KDM4E (0.36) | MEN1KMT2ATSHRL3MBTL1 | |
| SCHEMBL365206 | 0.81 | GP6 (0.36) | MEN1KMT2ATSHRCTSKTDP1 | |
| SCHEMBL15725999 | 0.81 | MEN1 (0.36) | MEN1KMT2AMAOAMAOBCHRM2 | |
| SCHEMBL28001128 | 0.80 | TSHR (0.41) | MEN1KMT2ATSHRCTSKTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9382253-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2016-07-05 | — | — | US | disclosed |
| US-20130112921-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2013-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130112921-A1 | METAL COMPLEXES | MCOLN2, MCOLN1, NCLN | MEN1 145/4885KMT2A 1833/4885TSHR 4843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.