SCHEMBL1493035

SCHEMBL1493035

CCCCOC(=O)CN=C=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.47
ALDH1A1 P00352 1/20 0.47
ATM Q13315 1/20 0.44
DGKA P23743 1/20 0.42
TSHR P16473 3/20 0.41
HPGD P15428 1/20 0.41
RAD52 P43351 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
FAAH O00519 1/20 0.40
HCAR2 Q8TDS4 1/20 0.39
HTR2C P28335 1/20 0.39
PRSS1 P07477 1/20 0.38
PRSS2 P07478 1/20 0.38
PRSS3 P35030 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
EPHX1 P07099 1/20 0.36
DNM1 Q05193 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL575780 0.88 NAAA (0.36) NAAAALDH1A1DGKATSHRRAD52
SCHEMBL11860209 0.86 NAAA (0.42) NAAAALDH1A1DGKATSHRRAD52
SCHEMBL10451052 0.81 DGKA (0.48) NAAAALDH1A1ATMDGKATSHR
SCHEMBL4106139 0.80 DGKA (0.52) NAAAALDH1A1ATMDGKATSHR
SCHEMBL8390835 0.79 ALDH1A1 (0.54) NAAAALDH1A1ATMDGKATSHR
SCHEMBL8378696 0.78 ALDH1A1 (0.52) NAAAALDH1A1ATMDGKATSHR
SCHEMBL21891774 0.78
Water SCHEMBL27286505 0.78 GAA (0.46) ALDH1A1TSHRTDP1MEN1KMT2A
SCHEMBL11438853 0.78 DGKA (0.58) NAAAALDH1A1DGKATSHRHTR2C
SCHEMBL10451645 0.78 DGKA (0.58) NAAAALDH1A1DGKATSHRHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5229243-A Addition polymer core, polyurethane or polythiourethane shell KAO CORPORATION (JP) 1993-07-20 US claimed
US-12577373-B2 Carbodiimide composition, curing agent composition, coating composition and resin cured product ASAHI KASEI KABUSHIKI KAISHA (JP) 2026-03-17 US disclosed
US-20240116897-A1 BENZOTHIAZOLE AND BENZIMIDAZOLE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2024-04-11 US disclosed
EP-4269394-A1 BENZOTHIAZOLE AND BENZIMIDAZOLE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT Korea Research Institute of Chemical Technology (KR) 2023-11-01 EP disclosed
CN-116829542-A Benzothiazole and benzimidazole derivatives, pharmaceutically acceptable salts, preparation method thereof and pharmaceutical composition containing same as active ingredient 韩国化学研究院 2023-09-29 CN disclosed
US-20230291010-A1 SOLID ELECTROLYTE, BATTERY, AND SOLID ELECTROLYTE MANUFACTURING METHOD PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2023-09-14 US disclosed
EP-3412740-B1 OPTICAL TRANSPARENT ADHESIVE SHEET, OPTICAL TRANSPARENT ADHESIVE SHEET PRODUCTION METHOD, LAMINATE, AND TOUCH PANEL-EQUIPPED DISPLAY DEVICE BANDO CHEMICAL IND (JP) 2023-07-12 EP disclosed
US-20230135772-A1 CARBODIIMIDE COMPOSITION, CURING AGENT COMPOSITION, COATING COMPOSITION AND RESIN CURED PRODUCT ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-05-04 US disclosed
EP-4130154-A1 CARBODIIMIDE COMPOSITION, HARDENER COMPOSITION, COATING COMPOSITION, AND CURED RESIN OBJECT Asahi Kasei Kabushiki Kaisha (JP) 2023-02-08 EP disclosed
EP-3357985-B1 OPTICALLY TRANSPARENT PRESSURE-SENSITIVE ADHESIVE SHEET, LAMINATE, PROCESS FOR PRODUCING LAMINATE, AND DISPLAY DEVICE WITH TOUCH PANEL BANDO CHEMICAL IND (JP) 2023-02-01 EP disclosed
EP-0042069-B1 METAL SALTS OF POLYACETYLENIC COMPOUNDS AND USES THEREOF ALLIED CORPORATION (US) 1985-02-06 EP disclosed
US-4466967-A NONTOXIC INSECTICIDES ROHM AND HAAS COMPANY (US) 1984-08-21 US disclosed
US-4452995-A TEMPERATURE INDICATORS; POLYDIACETYLENE GEL ALLIED CORPORATION (US) 1984-06-05 US disclosed
US-4439346-A THERMOCHROMIC ALLIED CORPORATION (US) 1984-03-27 US disclosed
US-4419360-A UREA OR THIOUREA DERIVATIVES ROHM AND HAAS COMPANY (US) 1983-12-06 US disclosed
US-4373032-A Metal salts of polyacetylenic compounds and uses thereof as ion exchange and thermochromic polymers ALLIED CORPORATION (US) 1983-02-08 US disclosed
EP-0042069-A2 Metal salts of polyacetylenic compounds and uses thereof ALLIED CORPORATION (US) 1981-12-23 EP disclosed
US-4171374-A 1-ARYLOXY-3-SUBSTITUTED UREIDO-ALKYLAMINO-2-PROPANOLS, ADRENERGIC BLOCKING AGENTS, CARDIAC STIMULANTS IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-10-16 US disclosed
US-4125534-A HIGH ENERGY RADIATION DOSAGE INDICATORS ALLIED CHEMICAL CORPORATION (US) 1978-11-14 US disclosed
US-3932318-A COPOLYMERS WITH ISOCYANATES, CRYOGENIC POLYMERIZATION, NONFLAMMABLE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577373-B2 Carbodiimide composition, curing agent composition, coating composition and resin cured product CD38, PARP9, MCCC2 NAAA 757/4885ALDH1A1 737/4885ATM 1103/4885
US-20240116897-A1 BENZOTHIAZOLE AND BENZIMIDAZOLE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT SIRT7, SIRT1, BRD7 NAAA 3827/4885ALDH1A1 776/4885ATM 2975/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.