SCHEMBL1493065

SCHEMBL1493065

C=CCC=C[SiH](Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
THRB P10828 1/20 0.32
KCNA3 P22001 1/20 0.31
LTA4H P09960 1/20 0.31
TSHR P16473 1/20 0.31
MMP9 P14780 1/20 0.31
GLA P06280 1/20 0.30
GAA P10253 1/20 0.30
HTT P42858 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2230239 0.78 LTA4H (0.35) AOC3KCNA3LTA4HTSHR
SCHEMBL5412050 0.71 CA4 (0.39) KCNA3LTA4HTSHR
SCHEMBL2228207 0.71 LTA4H (0.36) KCNA3LTA4HTSHR
SCHEMBL1782417 0.69 THRB (0.38) SMN1; SMN2KDM4EMEN1KMT2ATHRB
SCHEMBL5178753 0.69 LTA4H (0.40) AOC3SMN1; SMN2KDM4EMEN1KMT2A
SCHEMBL1493193 0.69 ALDH1A1 (0.32) TSHR
SCHEMBL27407629 0.68 AOC3 (0.62) AOC3SMN1; SMN2KDM4EMEN1KMT2A
SCHEMBL22654269 0.67 CYP3A4 (0.36) AOC3SMN1; SMN2KDM4EMEN1KMT2A
SCHEMBL1781213 0.67 ALDH1A1 (0.39) AOC3SMN1; SMN2KDM4EMEN1KMT2A
SCHEMBL1493207 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2470574-B1 PROCESS AND CATALYST SYSTEM FOR POLYDIENE PRODUCTION BRIDGESTONE CORP (JP) 2014-09-17 EP claimed
US-8765887-B2 Process and catalyst system for polydiene production BRIDGESTONE CORPORATION (JP) 2014-07-01 US claimed
EP-2470574-A2 PROCESS AND CATALYST SYSTEM FOR POLYDIENE PRODUCTION Bridgestone Corporation (JP) 2012-07-04 EP claimed
US-20120165484-A1 PROCESS AND CATALYST SYSTEM FOR POLYDIENE PRODUCTION BRIDGESTONE CORPORATION (JP) 2012-06-28 US claimed
WO-2011028523-A2 PROCESS AND CATALYST SYSTEM FOR POLYDIENE PRODUCTION BRIDGESTONE CORPORATION (JP) 2011-03-10 WO claimed
US-11767388-B1 Silicon-functionalized rubber THE GOODYEAR TIRE & RUBBER COMPANY (US) 2023-09-26 US disclosed
EP-2470574-B1 PROCESS AND CATALYST SYSTEM FOR POLYDIENE PRODUCTION BRIDGESTONE CORP (JP) 2014-09-17 EP disclosed
US-8765887-B2 Process and catalyst system for polydiene production BRIDGESTONE CORPORATION (JP) 2014-07-01 US disclosed
EP-2470574-A2 PROCESS AND CATALYST SYSTEM FOR POLYDIENE PRODUCTION Bridgestone Corporation (JP) 2012-07-04 EP disclosed
US-20120165484-A1 PROCESS AND CATALYST SYSTEM FOR POLYDIENE PRODUCTION BRIDGESTONE CORPORATION (JP) 2012-06-28 US disclosed
WO-2011028523-A2 PROCESS AND CATALYST SYSTEM FOR POLYDIENE PRODUCTION BRIDGESTONE CORPORATION (JP) 2011-03-10 WO disclosed