SCHEMBL14930769

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14930760	0.89	KDM4E (0.33)	EGFRKDM4EALDH1A1LMNAGAA
	SCHEMBL19439600	0.87	EGFR (0.42)	EGFRMEN1KMT2AMAPTNPC1
	SCHEMBL20272666	0.83	EGFR (0.33)	EGFR
	SCHEMBL24412825	0.78	DAO (0.45)	EGFRMEN1KMT2AKDM4EALDH1A1
	SCHEMBL7691202	0.76	MEN1 (0.35)	MEN1KMT2AKDM4EHPGDNPC1
	SCHEMBL8722327	0.74	MAPKAPK2 (0.41)	MEN1KMT2AHDAC1HDAC6KDM4E
	SCHEMBL7457137	0.74	ALDH1A1 (0.39)	MEN1KMT2AHDAC1HDAC6KDM4E
	SCHEMBL20154403	0.74	HSD17B1 (0.50)	HDAC1HDAC6MAPTIKBKB
	SCHEMBL23515510	0.73	HPGD (0.41)	EGFRMEN1KMT2AKDM4EALDH1A1
	SCHEMBL23312272	0.73	EGFR (0.33)	EGFRMEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.