Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.44 |
| ▸ | P2RY2 | P41231 | 6/20 | 0.39 |
| ▸ | PNP | P00491 | 2/20 | 0.39 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.38 |
| ▸ | POLG | P54098 | 1/20 | 0.38 |
| ▸ | UMPS | P11172 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | P2RY4 | P51582 | 5/20 | 0.37 |
| ▸ | P2RY6 | Q15077 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6465095 | 0.84 | P2RX3 (0.61) | P2RX3P2RY2FUT5UMPSTGM2 | |
| SCHEMBL14948862 | 0.84 | P2RX3 (0.61) | P2RX3P2RY2FUT5UMPSTGM2 | |
| SCHEMBL29868101 | 0.83 | P2RX3 (0.60) | P2RX3P2RY2FUT5UMPSTGM2 | |
| SCHEMBL14930996 | 0.79 | STING1 (0.47) | P2RY2FUT5P2RY4P2RY6 | |
| SCHEMBL15038134 | 0.76 | P2RY2 (0.53) | P2RX3P2RY2FUT5UMPSTGM2 | |
| SCHEMBL16160997 | 0.75 | UMPS (0.51) | P2RX3P2RY2PNPFUT5UMPS | |
| 8-Hydroxyguanosine SCHEMBL23633218 | 0.73 | PNP (0.68) | PNPMEN1KMT2A | |
| 8-Hydroxyguanosine SCHEMBL20419141 | 0.73 | PNP (0.68) | PNPMEN1KMT2A | |
| 8-Hydroxyguanosine SCHEMBL23982342 | 0.73 | PNP (0.68) | PNPMEN1KMT2A | |
| 8-Hydroxyguanosine SCHEMBL114651 | 0.73 | PNP (0.68) | PNPMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9428535-B2 | Modified nucleosides, nucleotides, and nucleic acids, and uses thereof | MODERNA THERAPEUTICS, INC. (US) | 2016-08-30 | — | — | US | disclosed |
| US-20130115272-A1 | MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF | modeRNA Therapeutics (US) | 2013-05-09 | — | — | US | disclosed |