SCHEMBL6465095

SCHEMBL6465095

Nc1nc2c([nH]c(=O)n2[C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]2O)c(=O)[nH]1

nearest known ligand 0.66

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
P2RX3 P56373 1/20 0.61
P2RY2 P41231 9/20 0.58
TGM2 P21980 1/20 0.54
UMPS P11172 1/20 0.52
P2RY6 Q15077 4/20 0.52
P2RY4 P51582 2/20 0.52
KRAS P01116 2/20 0.51
FUT5 Q11128 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14948862 1.00 P2RX3 (0.61) P2RX3P2RY2TGM2UMPSP2RY6
SCHEMBL29868101 0.99 P2RX3 (0.60) P2RX3P2RY2TGM2UMPSP2RY6
SCHEMBL15038134 0.91 P2RY2 (0.53) P2RX3P2RY2TGM2UMPSP2RY6
SCHEMBL16160997 0.90 UMPS (0.51) P2RX3P2RY2TGM2UMPSP2RY6
SCHEMBL5315097 0.85 TGM2 (0.58) P2RX3P2RY2TGM2P2RY6P2RY4
SCHEMBL5315091 0.85 TGM2 (0.58) P2RX3P2RY2TGM2P2RY6P2RY4
SCHEMBL17893049 0.85 PNP (0.66) P2RX3P2RY2TGM2P2RY6P2RY4
SCHEMBL14930893 0.84 P2RX3 (0.44) P2RX3P2RY2TGM2UMPSP2RY6
SCHEMBL154964 0.84 POLB (0.55) P2RX3P2RY2P2RY6P2RY4FUT5
SCHEMBL15794376 0.84 TGM2 (0.59) P2RX3P2RY2TGM2P2RY6P2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240309447-A1 METHODS AND KITS FOR PREPARING A SAMPLE COMPRISING ONE OR MORE RNA MOLECULES FOR SEQUENCING THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2024-09-19 US claimed
WO-2018119117-A1 METHODS OF PRODUCING CYCLIC DINUCLEOTIDES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-06-28 WO claimed
US-20140170689-A1 Modified Diguanylate Cyclase-Phosphodiesterase and Method for Enzymatic Production of Cyclic-diGMP THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2014-06-19 US claimed
US-20260028621-A1 METHOD FOR ENCODING DIGITAL DATA ON NUCLEIC ACIDS USING BIOLOGICAL PROCESSES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2026-01-29 US disclosed
EP-4534700-A2 REFERENCE LADDERS AND ADAPTORS Garvan Institute of Medical Research (AU) 2025-04-09 EP disclosed
EP-4527010-A1 METHOD FOR ENCODING DIGITAL DATA ON NUCLEIC ACIDS USING BIOLOGICAL PROCESSES Centre National de la Recherche Scientifique (FR) 2025-03-26 EP disclosed
US-20240309447-A1 METHODS AND KITS FOR PREPARING A SAMPLE COMPRISING ONE OR MORE RNA MOLECULES FOR SEQUENCING THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2024-09-19 US disclosed
CN-117797164-A Medicine for preventing and treating tumor and application thereof 北京医院 2024-04-02 CN disclosed
US-11920174-B2 RNA analysis by total hydrolysis and quantification of released nucleosides CureVac SE (DE) 2024-03-05 US disclosed
WO-2024036284-A1 GENERATION AND SELECTION OF AFFINITY REAGENTS NAUTILUS SUBSIDIARY, INC. (US) 2024-02-15 WO disclosed
US-20230392187-A1 REFERENCE LADDERS AND ADAPTORS GARVAN INSTITUTE OF MEDICAL RESEARCH (AU) 2023-12-07 US disclosed
WO-2023223068-A1 METHOD FOR ENCODING DIGITAL DATA ON NUCLEIC ACIDS USING BIOLOGICAL PROCESSES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2023-11-23 WO disclosed
EP-4103749-A1 REFERENCE LADDERS AND ADAPTORS Garvan Institute of Medical Research (AU) 2022-12-21 EP disclosed
US-20220351807-A1 BIOCOMPATIBLE NUCLEIC ACIDS FOR DIGITAL DATA STORAGE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2022-11-03 US disclosed
US-11446398-B2 Regulated biocircuit systems OBSIDIAN THERAPEUTICS, INC. (US) 2022-09-20 US disclosed
EP-4038616-A1 BIOCOMPATIBLE NUCLEIC ACIDS FOR DIGITAL DATA STORAGE Centre national de la recherche scientifique (FR) 2022-08-10 EP disclosed
WO-2018119117-A1 METHODS OF PRODUCING CYCLIC DINUCLEOTIDES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-06-28 WO disclosed
US-20140170689-A1 Modified Diguanylate Cyclase-Phosphodiesterase and Method for Enzymatic Production of Cyclic-diGMP THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2014-06-19 US disclosed
US-20050123937-A1 Methods for the electrochemical detection of target compounds UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL, THE 2005-06-09 US disclosed
WO-2004092708-A2 METHODS FOR THE ELECTROCHEMICAL DETECTION OF TARGET COMPOUNDS UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2004-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260028621-A1 METHOD FOR ENCODING DIGITAL DATA ON NUCLEIC ACIDS USING BIOLOGICAL PROCESSES NSUN2, RNMT, RNGTT P2RX3 676/4885P2RY2 496/4885TGM2 3888/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.