SCHEMBL1493142

SCHEMBL1493142

FB(F)c1ccccc1C(F)(F)F

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.40
TDP1 Q9NUW8 2/20 0.40
POLB P06746 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
IDO1 P14902 2/20 0.38
LMNA P02545 2/20 0.36
GAA P10253 1/20 0.36
TSHR P16473 1/20 0.36
HSD11B1 P28845 1/20 0.35
NFKB1 P19838 1/20 0.35
KIF11 P52732 1/20 0.35
KDM4E B2RXH2 1/20 0.35
ATM Q13315 1/20 0.35
HTR2C P28335 2/20 0.34
CA2 P00918 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31606418 0.82 ALDH1A1 (0.41) ALDH1A1TDP1POLBL3MBTL1MEN1
SCHEMBL813858 0.82 ALDH1A1 (0.41) ALDH1A1TDP1POLBL3MBTL1MEN1
SCHEMBL2408381 0.78 TRPV6 (0.42) ALDH1A1TDP1POLBL3MBTL1MEN1
SCHEMBL32674542 0.78 ALDH1A1 (0.39) ALDH1A1TDP1POLBL3MBTL1MEN1
SCHEMBL8851761 0.78 ALDH1A1 (0.39) ALDH1A1TDP1POLBL3MBTL1MEN1
SCHEMBL29410834 0.78 ENPP2 (0.41) ALDH1A1TDP1POLBL3MBTL1MEN1
SCHEMBL4288 0.78 ENPP2 (0.41) ALDH1A1TDP1POLBL3MBTL1MEN1
SCHEMBL8852075 0.78 ALDH1A1 (0.39) ALDH1A1TDP1POLBL3MBTL1MEN1
SCHEMBL7631820 0.75 TRPV6 (0.39) ALDH1A1TDP1POLBL3MBTL1MEN1
SCHEMBL63469 0.74 ALDH1A1 (0.52) ALDH1A1TDP1POLBL3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011031401-A2 LITHIUM NON-FLUORINATED AND FLUORINATED PHENYL TRIFLUORO BORATE SALTS FOR NON-AQUEOUS BATTERY ELECTROLYTES BROOKHAVEN SCIENCE ASSOCIATES LLC (US) 2011-03-17 WO disclosed