Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.42 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.40 |
| ▸ | ORAI2 | Q96SN7 | 2/20 | 0.40 |
| ▸ | ORAI3 | Q9BRQ5 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29410834 | 0.86 | ENPP2 (0.41) | TRPV6GAALMNAALDH1A1POLB | |
| SCHEMBL4288 | 0.86 | ENPP2 (0.41) | TRPV6GAALMNAALDH1A1POLB | |
| SCHEMBL2399014 | 0.86 | ALDH1A1 (0.37) | TRPV6ORAI1ORAI2ORAI3GAA | |
| SCHEMBL813858 | 0.80 | ALDH1A1 (0.41) | GAALMNAALDH1A1POLBTDP1 | |
| SCHEMBL31606418 | 0.80 | ALDH1A1 (0.41) | GAALMNAALDH1A1POLBTDP1 | |
| SCHEMBL28204350 | 0.79 | IDO1 (0.36) | TRPV6ORAI1ORAI2ORAI3GAA | |
| SCHEMBL1493142 | 0.78 | ALDH1A1 (0.40) | GAALMNAALDH1A1POLBTDP1 | |
| SCHEMBL28043678 | 0.77 | MEN1 (0.36) | TRPV6GAALMNAALDH1A1POLB | |
| SCHEMBL8852075 | 0.76 | ALDH1A1 (0.39) | GAALMNAALDH1A1POLBTDP1 | |
| SCHEMBL32674542 | 0.76 | ALDH1A1 (0.39) | GAALMNAALDH1A1POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6600066-B1 | Process for preparing perhalogenated monoorganoboranes or diorganoboranes which makes it possible to obtain these compounds under conditions which can readily be implemented in the industry is described. | BASELL POLYOLEFINE GMBH (DE) | 2003-07-29 | — | — | US | claimed |
| US-8853424-B2 | Protein cross-linking inhibitor | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2014-10-07 | — | — | US | disclosed |
| US-20110212919-A1 | PROTEIN CROSS-LINKING INHIBITOR | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2011-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212919-A1 | PROTEIN CROSS-LINKING INHIBITOR | BAZ2B, PRMT1, BRIX1 | TRPV6 4868/4885ORAI1 4605/4885ORAI2 3906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.