Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16719902 | 0.89 | TSHR (0.53) | TSHRSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL14933431 | 0.87 | TSHR (0.56) | TSHRSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL15687597 | 0.85 | LOXL2 (0.47) | TSHRSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL6798068 | 0.84 | P2RX1 (0.46) | TSHRSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL6800263 | 0.84 | TSHR (0.62) | TSHRSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL29959661 | 0.81 | TSHR (0.70) | TSHRSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL307312 | 0.81 | TSHR (0.70) | TSHRSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL8168008 | 0.79 | ALDH1A1 (0.50) | TSHRSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL16093623 | 0.79 | ABCB1 (0.49) | TSHRSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL16120112 | 0.77 | KMT2A (0.43) | TSHRSMN1; SMN2KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | TSHR 1272/4885SMN1; SMN2 1854/4885KMT2A 1496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.