Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15208727 | 0.82 | ALDH1A1 (0.44) | GAAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL14934256 | 0.82 | PARP1 (0.51) | GAAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL14934225 | 0.80 | MEN1 (0.39) | GAAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL15209356 | 0.80 | L3MBTL1 (0.54) | GAAALDH1A1SMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL15209122 | 0.79 | L3MBTL1 (0.53) | GAAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL15208504 | 0.78 | HTT (0.54) | GAAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL15218943 | 0.78 | RXFP1 (0.52) | GAAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL15208345 | 0.77 | SMN1; SMN2 (0.56) | GAAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL27918768 | 0.75 | SLC22A12 (0.37) | GAAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL15208595 | 0.75 | GAA (0.67) | GAAALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013064029-A1 | BENZOYLUREA DERIVATIVE WITH ANTICANCER ACTIVITY AND PREPARATION METHOD AND USE THEREOF | 浙江海正药业股份有限公司 (CN) | 2013-05-10 | — | — | WO | disclosed |