Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15208727 | 0.83 | ALDH1A1 (0.44) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL14934264 | 0.81 | PARP1 (0.52) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL15209063 | 0.81 | GAA (0.48) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL14934221 | 0.80 | GAA (0.40) | MEN1KMT2AGAAALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL15209798 | 0.80 | GAA (0.47) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL15218943 | 0.79 | RXFP1 (0.52) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL15208504 | 0.79 | HTT (0.54) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL15208345 | 0.78 | SMN1; SMN2 (0.56) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL15209356 | 0.76 | L3MBTL1 (0.54) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL15208595 | 0.76 | GAA (0.67) | MEN1KMT2AGAAALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013064029-A1 | BENZOYLUREA DERIVATIVE WITH ANTICANCER ACTIVITY AND PREPARATION METHOD AND USE THEREOF | 浙江海正药业股份有限公司 (CN) | 2013-05-10 | — | — | WO | disclosed |