Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27918761 | 0.83 | SLC22A12 (0.37) | SLC22A12GAAALDH1A1TSHRLMNA | |
| SCHEMBL27901147 | 0.81 | PARP1 (0.52) | SLC22A12GAAALDH1A1TSHRLMNA | |
| SCHEMBL15209356 | 0.76 | L3MBTL1 (0.54) | GAAALDH1A1TSHRLMNAMAPT | |
| SCHEMBL14934221 | 0.75 | GAA (0.40) | GAAALDH1A1LMNAMAPTKMT2A | |
| Hydrochloric Acid SCHEMBL15209122 | 0.75 | L3MBTL1 (0.53) | GAAALDH1A1TSHRLMNAMAPT | |
| SCHEMBL15208504 | 0.74 | HTT (0.54) | GAAALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL15218943 | 0.74 | RXFP1 (0.52) | GAAALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL28317899 | 0.73 | CASP6 (0.64) | TSHRLMNACASP6 | |
| SCHEMBL15208727 | 0.73 | ALDH1A1 (0.44) | GAAALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL15208345 | 0.73 | SMN1; SMN2 (0.56) | GAAALDH1A1LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103086925-B | Benzoyl urea derivative with active anticancer and its production and use | 浙江海正药业股份有限公司 | 2016-07-06 | — | — | CN | claimed |
| CN-103086925-A | Benzoyl urea derivatives having anticancer activity and their preparation method and use | ZHEJIANG HISUN PHARM CO LTD | 2013-05-08 | — | — | CN | claimed |
| CN-103086925-B | Benzoyl urea derivative with active anticancer and its production and use | 浙江海正药业股份有限公司 | 2016-07-06 | — | — | CN | disclosed |
| CN-103086925-A | Benzoyl urea derivatives having anticancer activity and their preparation method and use | ZHEJIANG HISUN PHARM CO LTD | 2013-05-08 | — | — | CN | disclosed |