Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.55 |
| ▸ | PLAU | P00749 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 2/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.45 |
| ▸ | LPL | P06858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16030765 | 1.00 | KEAP1 (0.55) | KEAP1NFE2L2PLAUCA1CA2 | |
| SCHEMBL14934888 | 0.88 | KEAP1 (0.46) | KEAP1NFE2L2PLAUCA1CA2 | |
| SCHEMBL29707329 | 0.88 | CA2 (0.52) | KEAP1NFE2L2CA1CA2CA9 | |
| SCHEMBL29707332 | 0.88 | CA2 (0.52) | KEAP1NFE2L2CA1CA2CA9 | |
| SCHEMBL9986027 | 0.87 | CA1 (0.53) | KEAP1NFE2L2CA1CA2CA9 | |
| SCHEMBL16247338 | 0.87 | KEAP1 (0.46) | KEAP1NFE2L2PLAUCA1CA2 | |
| SCHEMBL30543686 | 0.85 | HTT (0.51) | KEAP1NFE2L2CA1CA2CA9 | |
| SCHEMBL24142282 | 0.85 | LIPG (0.54) | KEAP1NFE2L2CA1CA2CA9 | |
| SCHEMBL25217470 | 0.84 | L3MBTL1 (0.42) | KEAP1NFE2L2PLAULMNASMN1; SMN2 | |
| SCHEMBL4823829 | 0.84 | POLB (0.54) | CA1CA2CA9NAMPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013067349-A1 | NOVEL CHEMISTRY USED IN BIOSENSORS | OHMX CORPORATION (US) | 2013-05-10 | — | — | WO | disclosed |