Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 8/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 8/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 6/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 6/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.30 |
| ▸ | TYMS | P04818 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14368418 | 0.81 | TGFBR1 (0.44) | TGFBR1FOLH1CA12CA1CA2 | |
| SCHEMBL2552690 | 0.77 | TGFBR1 (0.39) | TGFBR1CA12CA1CA2MMP1 | |
| SCHEMBL4187674 | 0.76 | FDPS (0.41) | TGFBR1CA12CA1CA2MMP1 | |
| SCHEMBL14937909 | 0.76 | MMP1 (0.44) | TGFBR1CA12CA1CA2MMP1 | |
| SCHEMBL2555697 | 0.75 | FDPS (0.42) | TGFBR1CA12CA1CA2MMP1 | |
| SCHEMBL4629779 | 0.74 | TGFBR1 (0.44) | TGFBR1ALDH1A1TDP1CA12CA1 | |
| SCHEMBL6103610 | 0.74 | FDPS (0.44) | TGFBR1S1PR1S1PR3S1PR2S1PR4 | |
| SCHEMBL2555753 | 0.74 | PLA2G2A (0.44) | S1PR1S1PR3S1PR2S1PR4 | |
| SCHEMBL14368417 | 0.73 | TGFBR1 (0.41) | TGFBR1 | |
| SCHEMBL976101 | 0.72 | TGFBR1 (0.42) | TGFBR1ANPEPALDH1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040602-B2 | Dental materials on the basis of highly acidic polymerizable bisphosphonic acids | IVOCLAR VIVADENT AG (LI) | 2015-05-26 | — | — | US | disclosed |
| US-9040602-B2 | Dental materials on the basis of highly acidic polymerizable bisphosphonic acids | IVOCLAR VIVADENT AG (LI) | 2015-05-26 | — | — | US | disclosed |
| US-20140296364-A1 | Dental Materials on the Basis of Highly Acidic Polymerizable Bisphosphonic Acids | IVOCLAR VIVADENT AG (LI) | 2014-10-02 | — | — | US | disclosed |
| US-20140296364-A1 | Dental Materials on the Basis of Highly Acidic Polymerizable Bisphosphonic Acids | IVOCLAR VIVADENT AG (LI) | 2014-10-02 | — | — | US | disclosed |
| WO-2013083734-A1 | DENTAL MATERIALS ON THE BASIS OF HIGHLY ACIDIC POLYMERISABLE BISPHOSPHONIC ACIDS | IVOCLAR VIVADENT AG (LI) | 2013-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296364-A1 | Dental Materials on the Basis of Highly Acidic Polymerizable Bisphosphonic Acids | PHOSPHO1, PTK2, ITGA1 | TGFBR1 2264/4885ANPEP 2998/4885FOLH1 938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.