Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.61 |
| ▸ | MEN1 | O00255 | 6/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14938497 | 1.00 | LMNA (0.62) | LMNAMAPTKDM4EKMT2AMEN1 | |
| SCHEMBL30193404 | 0.81 | MAPT (0.84) | LMNAMAPTKDM4EKMT2AMEN1 | |
| SCHEMBL2243293 | 0.81 | MAPT (0.84) | LMNAMAPTKDM4EKMT2AMEN1 | |
| SCHEMBL14938467 | 0.80 | LMNA (0.58) | LMNAMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL14938584 | 0.80 | MAPT (0.56) | LMNAMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL14938583 | 0.80 | MAPT (0.56) | LMNAMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL14938463 | 0.80 | LMNA (0.58) | LMNAMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL28632041 | 0.80 | MEN1 (0.68) | LMNAMAPTKDM4EKMT2AMEN1 | |
| SCHEMBL14938473 | 0.79 | SMN1; SMN2 (0.70) | LMNAMAPTKDM4EKMT2AMEN1 | |
| SCHEMBL14938474 | 0.79 | SMN1; SMN2 (0.70) | LMNAMAPTKDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013067646-A1 | PROCESS FOR THE SYNTHESIS OF BETA-AMINOCARBONYLS | UNIVERSITY OF OTTAWA (CA) | 2013-05-16 | — | — | WO | disclosed |