Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3118067 | 0.83 | ALDH1A1 (0.46) | ALDH1A1LMNAPRMT1CAPN1 | |
| SCHEMBL28780839 | 0.83 | L3MBTL1 (0.49) | ALDH1A1LMNAPRMT1CAPN1FFAR1 | |
| SCHEMBL17315470 | 0.82 | F2 (0.46) | ALDH1A1LMNA | |
| SCHEMBL3131696 | 0.80 | ALDH1A1 (0.46) | ALDH1A1LMNAPRMT1CAPN1 | |
| SCHEMBL3129382 | 0.79 | ALOX5 (0.47) | ALDH1A1LMNA | |
| SCHEMBL19117396 | 0.79 | CA2 (0.42) | KCNH2GPR119FFAR4 | |
| SCHEMBL1379944 | 0.78 | — | — | |
| SCHEMBL27690017 | 0.78 | CCR2 (0.38) | KCNH2GPR119PIK3CDPIK3CAPIK3CB | |
| SCHEMBL26937826 | 0.78 | DAO (0.47) | ALDH1A1LMNACAPN1FFAR1FFAR4 | |
| SCHEMBL14057721 | 0.77 | ALDH1A1 (0.41) | ALDH1A1LMNAPRMT1CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2776401-A1 | SUBSTITUTED PYRAZOLYL-BASED CARBOXAMIDE AND UREA DERIVATIVES BEARING A PHENYL MOIETY SUBSTITUTED WITH AN SO2-CONTAINING GROUP AS VANILLOID RECEPTOR LIGANDS | Grünenthal GmbH (DE) | 2014-09-17 | — | — | EP | claimed |
| WO-2013068464-A1 | SUBSTITUTED PYRAZOLYL-BASED CARBOXAMIDE AND UREA DERIVATIVES BEARING A PHENYL MOIETY SUBSTITUTED WITH AN SO2-CONTAINING GROUP AS VANILLOID RECEPTOR LIGANDS | Grünenthal GmbH (DE) | 2013-05-16 | — | — | WO | claimed |