Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14939566 | 0.82 | CA1 (0.56) | KMT2AMEN1GAACA1CA2 | |
| SCHEMBL14939682 | 0.81 | KMT2A (0.46) | KMT2AMEN1GAACA1CA2 | |
| SCHEMBL14939090 | 0.80 | CA1 (0.43) | KMT2AMEN1GAACA1CA2 | |
| SCHEMBL14940158 | 0.80 | NPSR1 (0.53) | KMT2AMEN1GAACA1CA2 | |
| SCHEMBL14940276 | 0.77 | PPIB (0.43) | KMT2AMEN1GAAMAPTKDM1A | |
| SCHEMBL14939632 | 0.76 | CA1 (0.43) | GAACA1CA2CA4CA7 | |
| SCHEMBL14939451 | 0.75 | MAPT (0.42) | GAACA1CA2CA7CA9 | |
| SCHEMBL14939057 | 0.74 | ALDH1A1 (0.52) | KMT2AMEN1GAACA1CA2 | |
| SCHEMBL14939711 | 0.73 | CYP2D6 (0.42) | CA1CA2CA7CA9BACE1 | |
| SCHEMBL7315657 | 0.72 | PDK2 (0.51) | KMT2AMEN1GAAACHEKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |