Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIB | P23284 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14939457 | 0.83 | NPSR1 (0.49) | LMNAMAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL14939771 | 0.82 | PPIB (0.47) | PPIBLMNAMAPTKMT2AMEN1 | |
| SCHEMBL14938966 | 0.82 | MAOB (0.45) | PPIBLMNAMAPTNPC1RAB9A | |
| SCHEMBL14938940 | 0.79 | NPSR1 (0.49) | LMNAMAPTKMT2ARAB9APKM | |
| SCHEMBL14938934 | 0.79 | LMNA (0.38) | LMNAKMT2AMEN1L3MBTL1UTS2R | |
| SCHEMBL14939783 | 0.79 | CASP6 (0.40) | LMNAMAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL14939565 | 0.78 | NPSR1 (0.44) | LMNAMAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL14938847 | 0.78 | HPGD (0.38) | LMNAMAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL14939005 | 0.77 | KMT2A (0.49) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL14939739 | 0.76 | NPSR1 (0.40) | LMNAMAPTKMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |