Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7596065 | 0.79 | THRB (0.67) | THRBKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL6652410 | 0.78 | KDM4E (0.52) | KDM4EALDH1A1CA1CA2LMNA | |
| SCHEMBL2805618 | 0.76 | DHODH (0.43) | KEAP1THRBKDM4EMEN1KMT2A | |
| SCHEMBL14914434 | 0.75 | KEAP1 (0.42) | KEAP1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL2466414 | 0.73 | RXFP1 (0.46) | THRBKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL10015552 | 0.71 | CYP1A2 (0.50) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL29771961 | 0.71 | KEAP1 (0.42) | KEAP1THRBKDM4EMEN1KMT2A | |
| SCHEMBL28857296 | 0.71 | KEAP1 (0.42) | KEAP1THRBKDM4EMEN1KMT2A | |
| SCHEMBL18186580 | 0.71 | HSD17B1 (0.46) | KEAP1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL188203 | 0.70 | ALDH1A1 (0.61) | KEAP1KDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068322-A1 | ALKENYL NAPHTHYLACETIC ACIDS FOR TREATING RESPIRATORY DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2013-05-16 | — | — | WO | disclosed |